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NCT ID: NCT05781906 Active, not recruiting - Clinical trials for Imumune Thrombocytopenia(ITP) Human Mass Balance

Human Mass Balance of [14C]HMPL-523 in Healthy Adult Male Chinese Subjects

Start date: February 8, 2023
Phase: Phase 1
Study type: Interventional

To evaluate the absorption, metabolism and excretion of HMPL-523 in healthy male Chinese subjects following multiple oral doses of HMPL-523 tablets followed by a single oral dose of [14C]HMPL-523 suspension

NCT ID: NCT05776745 Active, not recruiting - Epilepsy Clinical Trials

Study of Speech Function in Epileptic Patients Based on Stereoelectroencephalography Signal

Start date: March 20, 2022
Phase: N/A
Study type: Interventional

Based on stereoelectroencephalography model in the treatment of epilepsy patients, this study conducted language-related experimental studies without interfering with normal monitoring treatment. Meanwhile, voice data and intracranial electrophysiological data were collected for analysis. To study the mechanism related to the language function of patients, try to establish a model to decode the intracranial electrophysiological data related to language.

NCT ID: NCT05776732 Active, not recruiting - Tumour Clinical Trials

Effect of CaviionTM Precaution Medical Adhesive-related Skin Injury in Tumor Patients With PICC Catherizaion

Start date: March 7, 2022
Phase: N/A
Study type: Interventional

Malignant tumor patients are at high risk of medical adhesive-related skin injury(MARSI).MARSI can cause local skin ulceration, increase the difficulty of fixation and maintenance frequency, even cause unplanned extubation, and increase the pain and economic burden of the patient's re-installation.Malignant tumor patients with long-term PICC are prone to MARSI.CaviionTM can form a protective film on the skin.Applying CaviionTM before using the adhesive can effectively protect the skin and reduce the occurrence of rash.In China, CaviionTM is mostly used in infants and young children, but adults lack corresponding report and application data.Therefore, it is necessary to carry out corresponding randomized controlled study on adult patients, especially malignant tumors

NCT ID: NCT05776121 Active, not recruiting - Thyroid Eye Disease Clinical Trials

Study of ZB001 in Chinese Patients With Thyroid Eye Disease

Start date: May 10, 2023
Phase: Phase 1
Study type: Interventional

The investigational drug, ZB001 is a humanized IgG1κ monoclonal antibody targeting human IGF-1R. The study is designed to evaluate the efficacy, safety, tolerability, and pharmacokinetics(PK)/pharmacodynamics (PD) profile of ZB001 in Chinese patients with Thyroid Eye Disease.

NCT ID: NCT05774782 Active, not recruiting - Cerebral Aneurysm Clinical Trials

Parent Artery Reconstruction for Cerebral Aneurysms Using a Novel Flow Diverter With Surface Modification

Start date: March 27, 2023
Phase: N/A
Study type: Interventional

The primary objective of this trial is to evaluate the safety and efficacy of the cerebral flow diverter in the endovascular treatment of wide-necked cerebral aneurysms

NCT ID: NCT05773105 Active, not recruiting - Clinical trials for Advanced Hepatocellular Carcinoma

A Study of Cadonilimab Combined With Regorafenib in Patients With Advanced HCC

Start date: February 28, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the efficacy and safety of cadonilimab combined with regorafenib in patients with HCC who progressed on systemic therapy.

NCT ID: NCT05770180 Active, not recruiting - COVID-19 Clinical Trials

Phase II Clinical Trial of Recombinant COVID-19 Variant Vaccine (Sf9 Cell)

Start date: March 30, 2023
Phase: Phase 2
Study type: Interventional

A single-center, randomized, double-blind, controlled clinical trial to evaluate the safety and immunogenicity of booster vaccination of Recombinant COVID-19 variant vaccine (Sf9 cell) in healthy people aged 18 years and older after completing 2 or 3 doses of novel coronavirus inactivated vaccine (Vero cells)

NCT ID: NCT05765604 Active, not recruiting - COVID-19 Clinical Trials

Phase I Clinical Trial of Recombinant COVID-19 Variant Vaccine (Sf9 Cell) (WSK-V102)

Start date: March 14, 2023
Phase: Phase 1
Study type: Interventional

Subjects aged 18 and above who have been completed primary or booster vaccination of COVID-19 inactivated vaccines for 3 months or more, to conduct a randomized, parallel controlled, double-blind, single-center phase I clinical trial of Recombinant variant COVID-19 vaccine (Sf9 cell)(WSK-V102) to evaluate the safety, tolerance and immunogenicity of this vaccine in the study population.

NCT ID: NCT05764915 Active, not recruiting - Clinical trials for Advanced Solid Tumor

A Phase I Study of RGT-264 in Subjects With Advanced Solid Tumors

Start date: February 15, 2023
Phase: Phase 1
Study type: Interventional

This is a Phase 1 dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of RGT-264 as monotherapy in subjects with advanced solid tumors.

NCT ID: NCT05764629 Active, not recruiting - Diabetes Mellitus Clinical Trials

An Observational Study on Post-chronic Pancreatitis Diabetes Mellitus

Start date: September 1, 2021
Phase:
Study type: Observational

To explore the risk factors influencing glycemic status, optimized treatment, and prognosis of post-chronic pancreatitis diabetes mellitus (PPDM-C).