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NCT ID: NCT06439459 Completed - Skin Regeneration Clinical Trials

Skin Dermal Regeneration After Stromal Vascular Fraction Transplantation

SDR-SVF
Start date: February 15, 2023
Phase: N/A
Study type: Interventional

This study is a prospective, exploratory investigation aimed at exploring the efficacy of stromal vascular fraction (SVF) transplantation in treating exhaustion of dermal regenerative capacity during skin expansion. The dermal thickness, texture, and perfusion before and after SVF transplantation would be recorded and analyzed by a series of quantitative devices including laser 3D scanner, Doppler ultrasound, VISIA skin analyzer, CK skin analyzer, and indocyanine green angiography.

NCT ID: NCT06439433 Completed - Clinical trials for Papillomavirus Infections

ALA-PDT in Patients With CIN2 in p16-positivity and High-risk HPV Infection

Start date: May 31, 2021
Phase: Phase 2
Study type: Interventional

Efficacy and Safety of ALA-PDT in patients with cervical intraepithelial neoplasia grade 2 (CIN2) in p16-positivity and high-risk HPV infection.

NCT ID: NCT06439381 Not yet recruiting - Clinical trials for Chronic Rhinosinusitis

Long-term Safety and Efficacy of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps

Start date: June 2024
Phase: Phase 2
Study type: Interventional

This is a multicenter, randomized, continuing, Phase II expansion trial to evaluate the safety, efficacy, and immunogenicity of two doses of TQH2722 in the long-term treatment of severe chronic sinusitis with or without nasal polyps.

NCT ID: NCT06439368 Recruiting - Postoperative Pain Clinical Trials

Effect of Dezocine Combined With Sufentanil on the Quality of Postoperative Recovery and Analgesic Effect in Patients Undergoing Thoracic Surgery

Start date: January 5, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to evaluate the effect of dezocine combined with sufentanil on postoperative recovery quality and analgesic effect in patients undergoing thoracic surgery. It will also learn about the safety of dezocine. Researchers will compare drug dezocine to Sufentanil to see if dezocine works to Improve postoperative pain and recovery quality for patients. Participants will undergo elective surgery and receive PCIA postoperatively,taking dezocine combine with sufentanil,or only sufentanil respectively. Visit the VAS score after connecting the analgesic pump 24h and 48h,and evaluate the Quality of Recovery -15 score.

NCT ID: NCT06439342 Not yet recruiting - Clinical trials for Cytomegalovirus (CMV)

A Study of Maribavir in Chinese Adults With Cytomegalovirus (CMV) Infections

Start date: March 14, 2025
Phase: Phase 3
Study type: Interventional

The main aim of this study is to learn how safe maribavir is in Chinese adults who have undergone hematopoietic stem cell or organ transplantation and have a cytomegalovirus (CMV) infection and how well they tolerate treatment with maribavir. Other aims are to see how effective maribavir is in treating CMV infection and getting rid of the symptoms, the recurrence rate of CMV infection after treatment with maribavir and if the treatment is required again. Researchers will also check for changes (mutations) occurring in the virus which may cause treatment with maribavir to no longer work well or to not work at all (resistance to maribavir). The participants will be treated with maribavir for 8 weeks. During the study, participants will visit their study clinic 18 times.

NCT ID: NCT06438809 Recruiting - Clinical trials for Chronic Radiation Proctitis

Umbilical-Cord-Derived Mesenchymal Stem Cells Injection for Chronic Radiation Proctitis

Start date: May 24, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

A Phase I/II study to evaluate the safety and preliminary efficacy of human umbilical cord-derived mesenchymal stem cell injection for the treatment of chronic radiation proctitis.

NCT ID: NCT06438783 Recruiting - Osteosarcoma Clinical Trials

TQB2928 Injection Combined Anlotinib Hydrochloride Capsule in Recurrent/Metastatic Osteosarcoma and Other Solid Tumors

Start date: February 15, 2024
Phase: Phase 1
Study type: Interventional

This is a multicenter, open-label, multi-cohort Phase Ib trial to evaluate the efficacy and safety of TQB2928 injection combined with anlotinib hydrochloride capsule in patients with relapsed/metastatic osteosarcoma and other relapsed/metastatic solid tumors.

NCT ID: NCT06438757 Not yet recruiting - Allergic Asthma Clinical Trials

Trial of JYB1904 in Allergic Asthma

Start date: June 21, 2024
Phase: Phase 2
Study type: Interventional

This phase IIa trial is meant to evaluate the pharmacokinetics, pharmacodynamics and safety of JYB1904 in patients with allergic asthma.

NCT ID: NCT06438705 Recruiting - Lung Cancer Clinical Trials

99mTc Labeled FAP Targeted Molecular Probe in Early Diagnosis of Tumors

Start date: February 1, 2024
Phase:
Study type: Observational

At present, radiopharmaceuticals targeting FAP have been developed for the diagnosis and treatment of various tumors. Considering the problems of fast tumor tissue clearance and short retention time in small molecule FAP inhibitors based on quinoline rings, this project optimized their ligands and developed a new FAP targeted technetium labeled molecular imaging probe for SPECT/CT imaging research to evaluate its safety in clinical application and its effectiveness in tumor diagnosis.

NCT ID: NCT06438692 Recruiting - Heart Failure Clinical Trials

Ablation Strategies for Persistent Atrial Fibrillation Combined With Heart Failure

Start date: June 16, 2022
Phase: N/A
Study type: Interventional

(1) To evaluate the efficacy and safety of "2C3L" strategy combined with VOM anhydrous ethanol chemical ablation for persistent atrial fibrillation complicated with heart failure; (2) To evaluate the effectiveness of high-efficiency ablation of atrial fibrillation complicated with heart failure.