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NCT ID: NCT01755325 Suspended - Clinical trials for Chronic Myelogenous Leukemia

Phase III Study of Compound Formula Realgar-Indigo Naturalis Plus Imatinib Versus Placebo Plus Imatinib in Adult CML-CP Patients With Ph+

Start date: November 2012
Phase: Phase 3
Study type: Interventional

It is an open-label, randomized, double blind, placebo-controlled parallel-group, multi-center study to evaluate the efficacy and safety of Compound realgar formula Realgar-Indigo naturalis Tablet combined with Imatinib will be compared with imatinib alone in adult patients with diagnosed Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia in the chronic phase (CML-CP).

NCT ID: NCT01720901 Suspended - Clinical trials for Non-small Cell Lung Cancer

Increased Dose of Icotinib in Advanced None Small Cell Lung Cancer Patients After Routine Gefitinib Therapy

Start date: February 2013
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy and safety of increased dose of icotinib in advanced NSCLC patients who progressed after gefitinib therapy.

NCT ID: NCT01601093 Suspended - Clinical trials for Urinary Tract Infections

Study on Ceftazidime and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection

CAZ-SBT
Start date: November 2011
Phase: Phase 2
Study type: Interventional

In the proposed study, the investigators plan to evaluate the efficacy and safety of Ceftazidime Sodium and Sulbactam Sodium for Injection(2:1) for the treatment of respiratory and urinary tract acute bacterial infection.

NCT ID: NCT01443559 Suspended - Clinical trials for Porcine Corneal Xenograph

Xenogenic Keratoplasty From Porcine Cornea

XKFPC
Start date: September 2011
Phase: Phase 1
Study type: Interventional

Acellular porcine cornea is a valid substitution for human cornea because of its similar biological structure, corneal superficial curvature and good histocompatibility toward human. Facing the lack of human cornea donor, it is hypothesised that using acellular lamellar porcine cornea as an alternative of lamellar human cornea to treat infectious corneal ulcer.

NCT ID: NCT01233102 Suspended - Liver Cirrhosis Clinical Trials

Mesenchymal Stem Cells Treat Liver Cirrhosis

Start date: October 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate the efficacy of umbilical cord mesenchymal stem cells (MSCs) transfusion in the treatment of liver cirrhosis. Liver function will be monitored by serum analysis. The levels of serum alanine aminotransferase (ALT), total bilirubin (TB), prothrombin time (PT), prealbumin(PA) and albumin (ALB) will be examined at pre-transfusion, and 3 days to 2 years post-transfusion. Child-Pugh scores, Model for End-Stage Liver Disease scores and clinical symptoms will be assessed simultaneously.

NCT ID: NCT01132521 Suspended - Pancreatitis Clinical Trials

Ulinastatin in Severe Acute Pancreatitis

Start date: June 2010
Phase: Phase 4
Study type: Interventional

This study aims to evaluate the effect of ulinastatin in the treatment and prevention of organ failure in severe acute pancreatitis.

NCT ID: NCT00986284 Suspended - Clinical trials for Non Small Cell Lung Cancer

Epidermal Growth Factor Receptor (EGFR) Status Based Gefitinib Neoadjuvant Therapy in Non Small Cell Lung Cancer (NSCLC)

Start date: September 2009
Phase: Phase 2
Study type: Interventional

This study aims to investigate the efficacy and safety of gefitinib as neoadjuvant therapy in stage IIIA NSCLC patients.

NCT ID: NCT00892346 Suspended - Multiple Myeloma Clinical Trials

Single Autologous Stem Cell Transplantation Followed by Maintenance Therapy as Front-line Treatment for Myeloma

Start date: May 2009
Phase: Phase 3
Study type: Interventional

The clinical trial is to evaluate the efficacy of single autologous hematopoietic stem cell transplantation with standard conditioning of melphalan 200 mg/m2 followed by thalidomide maintenance in patients with newly-diagnosed myeloma after receiving 4-6 cycles of induction chemotherapy consisting of vincristin,adriamycin and dexamethasone (VAD) or thalidomide/dexamethasone between 18 to 65 years.

NCT ID: NCT00568529 Suspended - Gastric Cancer Clinical Trials

Combination of Capecitabine and Oxaliplatin in Patients With Relapsed or Refractory Gastric Cancer

Start date: October 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and overall survival of the regimen of XELOX (Xeloda and oxaliplatin combination) in the patients with relapsed and refractory gastric cancer.

NCT ID: NCT00563134 Suspended - Sepsis Clinical Trials

A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-negative Sepsis in Adult

Start date: October 2005
Phase: N/A
Study type: Interventional

Sepsis sometimes occurs in people who have a serious infection. It is caused by toxic substances (toxins) from bacteria and other germs entering your bloodstream. Most people with sepsis will recover with routine medical care before the illness gets more serious. However, in some people, sepsis does become more serious. This severe sepsis can cause damage to internal organs (such as your heart, lungs, kidneys, and liver) and can be life threatening. Special natural fats, (called 'lipoproteins') in our blood are thought to help protect us from the toxins produced by bacteria during sepsis. Levels of these lipoproteins are often low in people with sepsis and this may make it more difficult to recover from the disease. GR270773 is a new drug that has been developed to help the lipoproteins in protecting the body against toxins. GR270773 is made from purified fats and oils from the soyabean and does not contain cholesterol. This research study will test the safety (side effects) of GR270773 and whether or not it is effective in preventing complications in people with severe sepsis.