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NCT ID: NCT06260696 Completed - Obesity Clinical Trials

Assessing Health-Related Quality of Life and Willingness to Pay for Weight Management in Asia-Pacific by Gender

ASPECT - APAC
Start date: August 10, 2023
Phase:
Study type: Observational

The purpose of this survey is to collect information for scientific research and to identify the impact of overweight and obesity on health-related quality of life.

NCT ID: NCT06135948 Completed - L-thyroxine Clinical Trials

Impact of Increasing Levothyroxine Dose in Ramadan for UAE Patients With Hypothyroidism

Start date: March 15, 2022
Phase: Phase 4
Study type: Interventional

The study aims to compare the mean change in Thyroid Stimulating Hormone (TSH) levels among patients with hypothyroidism treated with an increased dose of L-thyroxine (treatment group) versus standard/regular dose of L-thyroxine (control group) during the month of Ramadan.

NCT ID: NCT06123585 Completed - Malocclusion Clinical Trials

Artificial Intelligence (AI) Empowered Smile Simulations: Do They Accurately Predict Actual Post Treatment Outcomes

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The aim of the present study is to assess the predictability of Invisalign® SmileView™ for digital AI smile simulation in comparison to actual smile treatment outcomes, using various smile assessment parameters.

NCT ID: NCT06055829 Completed - Clinical trials for Diabetes Mellitus, Type 1

The Adjustment of Doses in Diabetes Mellitus Type I

Start date: October 24, 2022
Phase:
Study type: Observational [Patient Registry]

The study was carried out in a diabetic patient who was starting a new approach for treatment. Previously the patient was treated with Novo-mix insulin injection twice per day, the physician decided to change the treatment strategy to be with three doses of novo-rapid insulin injections per day plus one injection of Lantus SoloStar in dinner. For two weeks we were monitoring the blood glucose level by the FreeStyle Libre sensor. Moreover, the right statistical technique was used for data analysis.

NCT ID: NCT05878301 Completed - Clinical trials for Postprandial Hyperglycemia

Postprandial Glucose, Insulin Response to Meal Sequence Among Healthy UAE Adults

Start date: June 9, 2023
Phase: N/A
Study type: Interventional

the goal of this Randomized controlled cross over trial is to compare the effects of meal sequences VPF meal vs. SMM on the incremental area under the curve of postprandial glucose response among healthy adults in the UAE. the main question it aims to answer is what is the effect of meal sequence of vegetable and protein first followed by carbohydrates (VPF) compared to a standard mixed meal (SMM) on the postprandial glucose level and insulin response among healthy adults in the UAE. Participants will consume two is caloric test meals in random order (SMM and VPF meal sequences) separated by a 7-10-day washout period then blood sample will be collected at fasting ,30min,60min and 120mon for glucose and insulin and hunger ration will be done as well .Researchers will compare the effect of the two meals on postprandial blood glucose, insuline and hunger rating.

NCT ID: NCT05862220 Completed - Clinical trials for D-Dimer as an Early Detector of Pulmonary Embolism

Correlation Between Computer Tomography Angiography and D-Dimer Level for the Diagnosis of Pulmonary Embolism

Start date: December 14, 2020
Phase:
Study type: Observational

A blood sample was taken before starting the patients on any thrombolytic treatment. The positivity threshold for D-Dimer was above 250 ng/ml. CTPA was performed after performing blood sampling. Patients with confirmed pulmonary embolisms were admitted to ICU for continued monitoring of vitals, consciousness level, and signs of tissue perfusion. Signs of shock or hemodynamic instability should be observed regularly. Patients were managed in the ICU with anticoagulants by parenteral use. The most commonly used items were Heparin, either Unfractionated (UFH) or low-molecular-weight heparin (LMWH).D-dimer levels can leverage to detect PE. D-dimer levels can help in guiding the option of CTPA and the initiation of treatment for patients with suspected PE.

NCT ID: NCT05848505 Completed - Clinical trials for Tonsillar Hypertrophy

Opioid-sparing Effect of Intranasal Dexmedetomidine

Start date: February 25, 2022
Phase: N/A
Study type: Interventional

Background: Management of postoperative pain in paediatric patients undergoing tonsillectomy remains a challenge that faces anesthesiologists in their daily practice. High dose of opioids are usually necessary and are responsible for side effects like nausea, vomiting, constipation, delayed hospital discharge and more importantly respiratory depression and sleep apnea. Dexmedetomidine is a selective alpha two agonist that has an analgesic and anxiolytic effect with minimal effects on respiratory drive. Goal of the study: The aim of this study is to assess the opioid sparing effect of preoperative intranasal dexmedetomidine as part of multimodal analgesia in the paediatric population undergoing tonsillectomy. Methods: This will be a prospective, randomised, controlled, double blinded clinical trial with 50 participants who will be randomised between two groups: dexmedetomidine group and control group. The dexmedetomidine group will receive intranasal dexmedetomidine in the preoperative holding area while the other group will receive the placebo. The primary endpoint will be the total fentanyl consumption in the perioperative period. Additionally, we will look at postoperative pain scores at 10, 30 and 60 minutes after recovery as well as the time to first opioid rescue analgesic and agitation scores as secondary endpoints. Blood pressure and hart rate will also be recorded throughout the study period.

NCT ID: NCT05722704 Completed - Cryotherapy Clinical Trials

Effect of Cryotherapy on Post-endodontic Pain

Start date: September 12, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare Cryotherapy with occlusal reduction in the reduction of post-endodontic pain in molars with symptomatic apical periodontitis. The main question it aims to answer is: Is there is a difference in post-endodontic pain intensity following cryotherapy or occlusal reduction in patients with symptomatic apical periodontitis on mandibular first molars? Participants will undergo root canal treatment including cryotherapy or post-operative occlusal reduction. Researchers will compare [Cryotherapy, occlusal reduction, and no intervention] to see the intensity of post-endodontic pain.

NCT ID: NCT05716724 Completed - Clinical trials for Diabetes Mellitus, Type 2

O-SEMA-Fast: A Research Study to Understand How Oral Semaglutide Works in People With Type 2 Diabetes Who Plan to Fast During Ramadan in the United Arab Emirates, Saudi Arabia, and Kuwait

O-SEMA-Fast
Start date: January 25, 2023
Phase:
Study type: Observational

The purpose of the study is to look at the change in blood sugar levels in people with type 2 diabetes who are using oral semaglutide and planning to fast during Ramadan. Participants will take oral semaglutide as prescribed by the study doctor. The study will last for about 5 months (20 weeks). Participants will be asked to complete a patient diary about how and when they take the oral semaglutide tablets. Participants will complete this diary during the study period as instructed by study doctor.

NCT ID: NCT05671770 Completed - Fabry Disease Clinical Trials

Study Based on Electronic Health RecOrds to Identify Patients at High-risk of Fabry DiseasE (HOPE Fabry)

Start date: July 28, 2023
Phase:
Study type: Observational

Primary objective: To estimate the prevalence of patients who are at high-risk for Fabry Disease (FD) in the Cleveland Clinic, Abu Dhabi (CCAD) United Arab Emirates (EMR) database from May 2016 to May 2022, according to the predictive algorithm (i.e., feasibility assessment eligibility criteria) Secondary objectives: - To estimate the prevalence of FD among patients at high-risk for FD (i.e., among enrolled patients) - To characterize the patient profile, overall and in Cohorts 1 and 2 - To describe the most common characteristics among positive FD patients and negative FD patients