Coronary Disease Clinical Trial
Official title:
The Red Wine Project: a Study of Ageing Indexes and Prevalence of Atherosclerosis in Regular Red Wine Consumers Versus Abstainers
The investigators will evaluate 100 regular red wine consumer men and 100 abstainers men
from 50 years-old to 70 years-old by coronary risk prevalence, mood status, anthropometric
measures, daily caloric ingest, lipid profile, carotid intimal media thickness, brachial
flow mediate dilatation, coronary tomographic angiography and leucocyte telomere length.
The sample size has been calculated expecting that regular red wine ingestion would lead to
a five year old younger vascular ageing indexes measured by carotid intimal media thickness,
coronary artery calcium scores and leucocyte telomere length longer than those abstainers
subjects at same age.
The investigators hypothesized that regular wine consumers present less coronary lesion and
coronary calcium score on coronary tomographic angiography, lower carotid intimal media
thickness and higher mean telomere length due the benefice of wine.
Status | Recruiting |
Enrollment | 200 |
Est. completion date | April 2011 |
Est. primary completion date | March 2011 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 50 Years to 70 Years |
Eligibility |
Inclusion Criteria: - healthy male, from 50 years-old to 70 years-old. Exclusion Criteria: - asiatic or with manifest atherosclerosis disease |
Observational Model: Case Control, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Brazil | Heart Insitute ( InCor) University of Sao Paulo | Sao Paulo |
Lead Sponsor | Collaborator |
---|---|
University of Sao Paulo |
Brazil,
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