Coronary Artery Disease Amenable to Bypass Graft Surgery Clinical Trial
Official title:
Graft Patency Following Off-Pump CABG Vs. On-Pump CABG Using 64 MDCT Bypass Graft CT Angiography
The purpose of this study is to compare graft patency rates following coronary artery bypass graft surgery performed by beating heart vs. conventional techniques using cardiac CT scanning to evaluate the bypass grafts.
The issue of whether to perform conventional CABG or off-pump CABG continues to be the
subject of debate. Controversy remains regarding the appropriateness of applying OPCAB to
all patients as opposed to selected sub-populations.
The main strategy of CABG is to obtain complete revascularization with the least morbidity
and highest long-term patency rates. Current medical literature is conflicted regarding
graft patency rates in OPCAB vs. conventional CABG. Data is also limited due to patient
refusal for conventional angiography to assess grafts following surgery. Cardiac computed
tomography (CT) offers a non-invasive method to assess graft patency that is 100% accurate
for the diagnosis of graft patency vs. occlusion. This study is a prospective randomized
controlled trial evaluating graft patency in on-pump vs. off-pump CABG using cardiac CT
scanning. The study hypothesis is that graft patency rates will be equivalent between the
two techniques.
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Treatment