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Corneal Opacity clinical trials

View clinical trials related to Corneal Opacity.

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NCT ID: NCT06174376 Not yet recruiting - Corneal Opacity Clinical Trials

Clinical Outcomes of the Gore Synthetic Cornea Device

Start date: July 1, 2024
Phase: N/A
Study type: Interventional

Study objective is to evaluate the initial safety and effectiveness of the GORE Synthetic Cornea Device in the treatment of loss of corneal clarity in patients who are candidates for corneal transplantation

NCT ID: NCT06000150 Completed - Corneal Opacity Clinical Trials

Characteristics of Trachomatous Corneal Opacity in Fayoum University Hospital

Trachoma
Start date: February 1, 2022
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to assess the characteristics of trachomatous corneal opacity in patients with signs of trachoma using Anterior segment Optic coherence tomography and Pentacam

NCT ID: NCT05694247 Recruiting - Corneal Disease Clinical Trials

Study to Evaluate the Clinical Safety and Performance of the CorNeat KPro for Treatment of Corneal Blindness

Start date: March 2024
Phase: N/A
Study type: Interventional

A Single Arm, Pivotal, Open Label, Multicenter Clinical Investigation to Evaluate the Clinical Safety and Performance of the CorNeat Keratoprosthesis, for Treatment of Corneal Blindness

NCT ID: NCT05345652 Not yet recruiting - Keratoconus Clinical Trials

Evaluation Of Deep Anterior Lamellar Keratoplasty By Anterior Segment Ocular Coherence Tomography

Start date: May 1, 2022
Phase:
Study type: Observational

Investigators' research is concerned observing the post-operative anterior segment OCT changes throughout the post- operative follow up of the patient and relating to improve the visual outcome of the surgery which is the goal of surgery

NCT ID: NCT05313425 Recruiting - Clinical trials for Photorefractive Keratectomy

Effect of Ectoine After Photorefractive Keratectomy (PRK).

Start date: January 1, 2022
Phase:
Study type: Observational

This is a comparative, open label, parallel group, non interventional study aims to assess the effect of Ectoine containing eye drops on stromal haze, pain and epithelial healing after Photorefractive keratectomy (PRK). The patient apply Ectohylo eye drops (Ectoine +Sodium Hyauronate) in the right eye and Polyfresh Extra eye drops (Carboxymethyl cellulose + Sodium Hyauronate ) in the left eye plus the routine post PRK treatment in both eyes. Post operative pain , epithelial healing and corneal densitometry is observed in both eyes.

NCT ID: NCT05072977 Recruiting - Myopia Clinical Trials

Photorefractive Keratectomy (PRK) : Comparison of Corneal Haze Between Two Modes of De-epithelialisation (Laser Versus Manual Alcohol)

H-TransPKR
Start date: February 9, 2022
Phase: N/A
Study type: Interventional

surgical correction of ametropia. A number of improvements have been introduced to overcome the side effects and complications such as corneal haze, epithelial irregularities induced by wound healing, pain and delayed visual acuity recovery associated with PRK surgery. During traditional PRK, the corneal epithelium is mechanically debrided before stromal ablation is performed. Alcohol PRK is frequently used as an alternative to mechanical epithelial debridement and is considered simpler and faster. Transepithelial PRK (TransPRK) is a new method in which the corneal epithelium is photoablated by the laser in one step using a specific ablation profile. This study attempts to establish a means of quantitatively and objectively measuring corneal haze, using patented software based on optical coherence tomography (OCT) of the cornea. This will confirm or refute the hypothesis of a lower occurrence of corneal haze after TransPRK (experimental group) versus PRK with alcohol (control group). Each patient will have one eye randomised to one of the two groups being compared.

NCT ID: NCT05014269 Completed - Senile Cataract Clinical Trials

Phacoemulsification in Patients With Corneal Opacities

Start date: January 1, 2015
Phase:
Study type: Observational

In this retrospective case series, the feasibility of performing phacoemulsification using slit illumination in eyes with corneal opacity was assessed.

NCT ID: NCT04752969 Completed - Corneal Opacity Clinical Trials

The Effect of Thyroid Hormon Levels on the Corneal Measures

Start date: June 15, 2020
Phase:
Study type: Observational

In this cross-sectional comparative study, it is aimed to investigate the topographic measurements,aberrometrics and densitometrics values of corneas in hypothyroid and hyperthyroid patients compared to healthy individuals. A number of 20 hypothyroid patients (group I), 20 hyperthyroid patients (group II), and 20 age-matched healthy controls (group III) have been recruited. The Pentacam high resolution imaging system is used to determine corneal topographic measurements,aberrometry and densitometry.

NCT ID: NCT04485858 Terminated - Corneal Disease Clinical Trials

First in Human (FIH) Study to Assess Safety and Efficacy of the CorNeat KPro for the Treatment of Corneal Blindness

Start date: January 3, 2021
Phase: N/A
Study type: Interventional

Prospective, open label, single arm, First in Human (FIH) clinical study to assess safety and efficacy of the CorNeat Keratoprosthesis, a synthetic cornea, for the treatment of corneal blindness

NCT ID: NCT04120389 Recruiting - Cataract Clinical Trials

Efficacy of an Ocular Bandage Contact Lens for the Treatment of Dry Eye After Complicated and Combined Cataract Surgery

Start date: March 13, 2020
Phase: N/A
Study type: Interventional

To study the efficacy of an ocular bandage contact lens for the treatment of dry eye after complicated and combined cataract surgery