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Chronic Obstructive Pulmonary Disease clinical trials

View clinical trials related to Chronic Obstructive Pulmonary Disease.

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NCT ID: NCT03940040 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

High Flow Nasal Oxygen Versus Usual Care in COPD Pulmonary Rehabiliation

Start date: May 28, 2019
Phase: N/A
Study type: Interventional

To compare the effects of high flow nasal oxygen with usual care during an outpatient 6-week pulmonary rehabilitation program after hospitalization for COPD exacerbation.

NCT ID: NCT03900195 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

The Effectiveness of Bottle-PEP in Chronic Obstructive Pulmonary Disease

Start date: January 21, 2019
Phase: N/A
Study type: Interventional

The effectiveness of Bottle PEP in patients with Chronic Obstructive Pulmonary Disease

NCT ID: NCT03893409 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

GIRH Chronic Obstructive Pulmonary Disease Observational Study

Start date: August 10, 2018
Phase:
Study type: Observational

The purpose of this study is to establish the large COPD cohort and biological database in China, aiming for precision medicine to optimize diagnosis and treatment choices.

NCT ID: NCT03890224 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Respiratory Support in Chronic Obstructive Pulmonary Disease (COPD) Patients

Start date: July 4, 2019
Phase: N/A
Study type: Interventional

The hypothesis of this study is that any of 3 modalities of home non- invasive ventilation (NIV) compared to 'no NIV' (=hospital NIV) will reduce re-admission to hospital or death in COPD patients who remain persistently hypercapnic following an exacerbation requiring NIV.

NCT ID: NCT03889964 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Exercise Capacity in COPD

Start date: March 1, 2019
Phase:
Study type: Observational

In this study, cardiopulmonary exercise will be assessed to characterize the relevance of severity of COPD and coexisting cardiovascular comorbidities for exercise capacity.

NCT ID: NCT03873298 Recruiting - COPD Clinical Trials

Inhaled NO in IPF and COPD During 6 Minute Walk Test

Start date: March 4, 2019
Phase: Phase 2
Study type: Interventional

Our objective is to evaluate the influence of inhaled NO on the saturation and exercise capacity of patients with COPD and IPF. each participant will undergo two six minute walk tests, one with inhaled NO and the other with placebo.

NCT ID: NCT03863717 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Investigation of the Effectiveness of Upper Limb Exercise in COPD Patients

Start date: December 14, 2017
Phase: N/A
Study type: Interventional

The aim of the study is to investigate the efficacy of upper limb exercise training in Chronic Obstructive Pulmonary Disease (COPD) patients. For the purpose of the study, a controlled trial will be conducted within Respiratory Clinic of Nicosia General Hospital. The sample will be divided in two groups. The intervention group will participate in a pulmonary rehabilitation program which includes upper and lower extremities exercises, with addition of arm ergometer. The second group (control group) will participate in the same program but without arm ergometer training. The study's hypothesis is that the intervention group will improve the outcome measures significantly better than the control group.

NCT ID: NCT03844711 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Transcutaneous Electrical Diaphragmatic Stimulation and Inspiratory Muscle Training in Patients With COPD Exacerbated

Start date: February 16, 2019
Phase: N/A
Study type: Interventional

Chronic Obstructive Pulmonary Disease (COPD) is characterized by chronic airflow limitation, a qualification of impairment of respiratory muscle function, including hyperinflation and muscle weakness. Thus, pulmonary rehabilitation is indicated for patients and is recommended for even the most severe cases. However some patients do not conclude conventional rehabilitation protocols, due to exercise intolerance, are then an electrical estimation and muscle training respiratory adjuvant treatments for patients. and little has been explored about the effects and methodologies of using transcutaneous electrical diaphragmatic stimulation (TEDS) in healthy subjects. The objective of this study on stage I is to evaluate the acute effect of transcutaneous electrical diaphragmatic stimulation on respiratory muscle strength, cardiac variability, thickness, resistance, mobility and diaphragmatic activation comparing different frequencies of electrical stimulation in healthy individuals. The objective of this study on stage II is to evaluate the effects of transcutaneous electrical diaphragmatic stimulation, compared to inspiratory muscle training on respiratory muscle strength, security of the technics, thickness and diaphragmatic function in healthy individuals.The objective of this study on stage III is to evaluate the effects of transcutaneous electrical diaphragmatic stimulation, compared to IMT on respiratory muscle strength, lung function, thickness and diaphragmatic function in patients with exacerbated chronic obstructive pulmonary disease. The study was approved by the Research Ethics Committee of the Hospital de Clinicas of Porto Alegre (CAEE: 80271517.2.0000.5327).

NCT ID: NCT03840928 Recruiting - Obesity Clinical Trials

PatientSpot Formerly Known as ArthritisPower

Start date: April 1, 2015
Phase:
Study type: Observational [Patient Registry]

Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with rheumatoid arthritis (RA), spondyloarthritis (SpA), other musculoskeletal conditions, chronic neurological conditions like migraine, chronic pulmonary conditions like Chronic Obstructive Pulmonary Disease (COPD), asthma, autoimmune dermatological conditions such as psoriasis, and other chronic inflammatory or immune-mediated conditions. In addition, since patients with chronic conditions often have other co-morbidities like cardiovascular health and obesity-related metabolic disorders, these conditions will also be included. Participants will provide information from their smartphones or personal computers. The information will be used by researchers and clinicians to help patients and their providers make better, more informed decisions about treatment of chronic conditions.

NCT ID: NCT03824834 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Morphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent Breathlessness

MorEx
Start date: August 6, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to explore the role of low-dose immediate-release oral morphine as a novel adjunct pharmacotherapy to enable symptomatic adults with advanced chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD) to exercise at higher intensities for longer durations and maximize the psycho-physiological benefits of a supervised exercise training program. We hypothesize that, compared to placebo, exercise training with oral morphine will result in relatively greater improvements in exercise endurance time and intensity ratings of perceived breathlessness during constant-load cardiopulmonary cycle exercise testing (CPET) at 75% of peak power output (PPO).