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Contraceptive Usage clinical trials

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NCT ID: NCT03571932 Completed - Contraception Clinical Trials

Assessment of Family Planning and Immunization Service Integration in Liberia

Start date: November 2016
Phase:
Study type: Observational

This is a mixed methods process evaluation of a programmatic intervention to integrate family planning and immunization services at health facilities in Lofa and Grand Bassa counties in Liberia. MCSP used a longitudinal, pair-matched design to monitor the effect of integrating immunization and FP services on utilization of FP and routine immunization services. In Lofa and Grand Bassa counties, 36 facilities were pair-matched to intervention and comparison sites based on predetermined criteria. After approximately 9 months of implementation, MCSP conducted a qualitative study employing key informant interviews (KIIs) and focus group discussions (FGDs) at intervention and comparison sites, and with district-, county-, and national-level MOH supervisors and managers.

NCT ID: NCT03467347 Completed - Healthy Clinical Trials

PK Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel

Start date: July 17, 2018
Phase: Phase 1
Study type: Interventional

This is a Phase I single-center, two-arm, open-label, randomized study in healthy HIV-negative women to evaluate the pharmacokinetics, safety, and bleeding patterns associated with 90-day use of matrix vaginal rings containing 200 mg Dapivirine and 320 mg Levonorgestrel.

NCT ID: NCT03419728 Active, not recruiting - Contraceptive Usage Clinical Trials

Federal Evaluation of Selected Programs for Expectant and Parenting Youth

PEPY
Start date: June 2015
Phase: N/A
Study type: Interventional

Under contract to the U.S. Department of Health and Human Services (DHHS), Mathematica Policy Research is conducting an impact study of Healthy Families Healthy Futures in Houston, Texas for a Federal Evaluation of Programs for Expectant and Parenting Youth (PEPY). The impact study will be designed to address three main questions: - Was the program successful in exposing participants to program content, such as information about methods of birth control? - Was the program successful at improving short-term outcomes, such as use of a LARC and intention to space births? - To what extent did treatment youth receive the intended program components?

NCT ID: NCT03418363 Completed - Contraceptive Usage Clinical Trials

How DHEA Supplements Affect Coagulation in Women Using Birth Control Pills

COC+DHEA
Start date: January 16, 2018
Phase: Phase 4
Study type: Interventional

A randomized study is to learn more about how a supplement called DHEA (dehydroepiandrosterone) affects clotting factors in women taking combined oral contraceptive pills. Current research suggests that the progestin hormone in a specific type of birth control pill may increase a woman's blood clot risk. However, it is unknown exactly how the progestin causes the increased risk. This study aims to learn if taking a daily dose of supplemental androgen (dehydroepiandrosterone, or DHEA) in addition to birth control pills containing DRSP affects proteins related to coagulation.

NCT ID: NCT03404284 Completed - Contraception Clinical Trials

Assessment of Family Planning and Immunization Service Integration in Malawi

Start date: June 2016
Phase: N/A
Study type: Observational

This is a mixed methods process evaluation of a programmatic intervention to integrate family planning and immunization services at health facilities and through outreach services in Dowa and Ntchisi districts of Malawi. The study involved qualitative methods (in depth interviews and focus group discussions with service providers, mothers and fathers of infants <1 year, and supervisors and program managers) as well as secondary analysis of service statistics for family planning and immunization services and of supervision reports.

NCT ID: NCT03402217 Completed - Contraceptive Usage Clinical Trials

Patient Centered Postpartum Contraception App

Start date: May 18, 2018
Phase:
Study type: Observational

This study will evaluate a smart phone-based application ("app") designed to inform pregnant women ages 15-25 about their contraception options. The goal of this research will be to evaluate the usability, feasibility and acceptability of this app.

NCT ID: NCT03400449 Completed - Contraceptive Usage Clinical Trials

Video Versus Conversational Contraceptive Counseling During Maternity Hospitalization

Start date: April 28, 2015
Phase: N/A
Study type: Interventional

A randomized trial comparing LARC uptake and satisfaction after either video or conversational-based contraceptive counseling for pregnant women in labor.

NCT ID: NCT03383185 Completed - Metabolic Syndrome Clinical Trials

Metabolic Profile of Users of Hormonal and Non-hormonal Contraceptives

Start date: January 1, 2010
Phase: N/A
Study type: Observational

Evaluation of metabolic profile of users of hormonal and non-hormonal contraceptives during five years follow-up

NCT ID: NCT03336346 Completed - HIV Infections Clinical Trials

Effect of Dolutegravir on Etonogestrel Levels in HIV-infected Women in Botswana

Start date: November 15, 2017
Phase:
Study type: Observational

The primary aim is to assess if etonogestrel (ENG) implant users taking dolutegravir (DTG) have a 20% or greater change in their ENG plasma levels, compared to women taking no antiretroviral therapy (ART). A secondary aim is to assess whether ENG implant users taking dolutegravir have significantly higher ENG plasma levels than ENG implant users taking efavirenz. This is a cross-sectional, non-randomized evaluation to compare ENG levels between 3 and 12 months post-implant insertion in three groups of women: 1) women using DTG-based ART (n=90), 2) women using EFV-based ART (n=90), and 3) women using no ART (not HIV infected) (n=90). This study will be conducted in Botswana in Southern Africa among women using the ENG implant, and involves a one-time collection of blood and questionnaire.

NCT ID: NCT03279120 Completed - Contraceptive Usage Clinical Trials

Safety, PK, and PD Study of IVRs Releasing TFV and LNG

TFV/LNG IVR
Start date: September 28, 2017
Phase: Phase 1
Study type: Interventional

This multi-center Phase I study is designed to characterize the safety, PK, and PD of TFV/LNG IVR to assess systemic and genital tract bioavailability in healthy women. The IVRs to be used in the study are TFV/LNG IVR (8-10mg per day/20μg per day) or placebo IVR. Samples will be obtained before, during and after 90 days of continuous or interrupted IVR use.