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Contraception clinical trials

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NCT ID: NCT05252052 Completed - Contraception Clinical Trials

Contraception Perspectives in Adolescents in Haiti

Start date: March 22, 2021
Phase:
Study type: Observational

The overall goal of this study is to assess facilitators and barriers to contraception with a focus on long-acting reversible contraception (LARC) among adolescents and health care providers (HCPs) in rural Haiti. The investigator plans to accomplish the following objectives:

NCT ID: NCT05040282 Completed - Contraception Clinical Trials

The Amenorrhea With Etonogestrel Implant

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

The etonogestrel subdermal implant has been available worldwide for more than 15 years. The action of etonogestrel subdermal implant is principal via suppression of ovulation, but it also has effects on cervical mucus and in some women induces suppression of endometrial proliferation. Several studies have confirmed its high efficacy and convenience. The uterine bleeding problems and in particular irregular bleeding and amenorrhea are major side effects of etonogestrel subdermal implant. A considerable number of patients request early removal due to bleeding changes. Amenorrhea occurs in about 22% in etonogestrel subdermal implant users. Despite the presence of many studies that reported the prevalence of etonogestrel subdermal implant-associated bleeding, little is known about the predictive factors affecting menstrual bleeding patterns especially amenorrhea after etonogestrel subdermal implant insertion. These predictive factors should be provided prior to the etonogestrel subdermal implant insertion which may improve acceptance and continuation of etonogestrel subdermal implant.

NCT ID: NCT05002738 Completed - Contraception Clinical Trials

Desogestrel-containing COCP Pharmacokinetic Validation Study

Start date: September 10, 2021
Phase: Phase 4
Study type: Interventional

This study aims to validate prior pharmacokinetic research with combined oral contraceptive pill users that supports utilizing a 24-hour trough concentration as an accurate proxy for the intensive pharmacokinetic parameter of area under the curve (gold standard pharmacokinetics). The original pharmacokinetic studies were performed with a levonorgestrel-containing oral contraceptive pill and we aim to duplicate those findings with a desogestrel-containing oral contraceptive pill.

NCT ID: NCT04965116 Completed - Contraception Clinical Trials

Progestin-Only Pill Use and Breastfeeding Study

Start date: October 25, 2021
Phase: Phase 4
Study type: Interventional

This study will assess the impact of early initiation (less than one week postpartum) and delayed initiation (4 weeks postpartum) of two types of progestin-only contraceptive pills (POPs) on maternal, breastmilk, and infant outcomes.

NCT ID: NCT04879745 Completed - Contraception Clinical Trials

MyVoice:Rheum Decision Aid for Women With Rheumatic Diseases

Start date: July 29, 2021
Phase: N/A
Study type: Interventional

This is a pilot trial to assess feasibility and acceptability of MyVoice:Rheum vs. a patient pamphlet among female patients ages 18-44 (n=40) who receive rheumatology care. • Hypothesis: MyVoice:Rheum will be feasible and acceptable to patients who receive rheumatology care.

NCT ID: NCT04861870 Completed - Contraception Clinical Trials

Bandebereho 6 Year Follow up RCT in Rwanda

Start date: June 15, 2021
Phase: N/A
Study type: Interventional

This study seeks to conduct a six-year follow-up of the Bandebereho randomized control trial (RCT) to assess the longer-term impact of the gender-transformative Bandebereho couples intervention on participating men, women, and their children. The Bandebereho program was implemented by the Rwanda Men's Resource Centre (RWAMREC) and Promundo-US, in collaboration with the Rwanda Ministry of Health and local authorities between 2013 and 2015. A two-arm RCT collected three rounds of data from 1,199 couples (575 treatment; 624 control) starting in 2015-16: baseline (pre-intervention), 9 month follow-up, and 21-month follow-up. The findings at 21-months demonstrated significant impacts of the intervention on multiple gender and health-related outcomes. This study will conduct surveys with men enrolled in the RCT and their female partners 6 years after the intervention, to assess its long-term impact on reproductive and maternal health, gender attitudes and household dynamics, intimate partner violence, mental health and wellbeing, parenting, and child development. In addition, child assessments will be conducted with a sub-sample of 800 children aged 4 to 7 years to directly assess early childhood development outcomes.

NCT ID: NCT04825236 Completed - Cystic Fibrosis Clinical Trials

MyVoice:CF Decision Aid for Women With Cystic Fibrosis

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

This project is a single-center feasibility study of MyVoice:CF, a patient-facing, web-based decision aid. Aim 1) Assess the acceptability, feasibility, and usability of MyVoice:CF for women with CF and multidisciplinary adult CF providers. Aim 2) Assess the preliminary efficacy of MyVoice:CF related to patient-provider communication, shared decision-making, knowledge, and self-efficacy for women with CF related to reproductive health concerns.

NCT ID: NCT04778514 Completed - HIV Infections Clinical Trials

A Crossover Acceptability Study Assessing a DPP Capsule for HIV and Pregnancy Prevention

952
Start date: December 7, 2022
Phase: N/A
Study type: Interventional

The study design is a single-site, two-arm, randomized, open-label crossover trial in 30 AGYW aged 16-24 in Chitungwiza (Harare), Zimbabwe. The aim of the study is to assess the acceptability of, preference for, and adherence to a single DPP capsule containing one PrEP tablet and one COC tablet compared to two separate tablets (FTC/TDF and EE/LNG), each taken for three consecutive menstrual cycles for a total of 24 weeks among current COC users.

NCT ID: NCT04767139 Completed - Contraception Clinical Trials

EPI, a Missed Opportunity for Postpartum Family Planning Utilization

EPI
Start date: February 1, 2020
Phase:
Study type: Observational

The global unmet need for postpartum family planning remains high, while immunization services are among the most widely utilized health services. Most women in the extended postpartum period want to delay or avoid future pregnancies but many are not using a modern contraceptive method. Establishing systematic screening, counseling, and referral systems from different contact points particularly from infant immunization units may improve family planning access and uptake in the extended postpartum period. Hence, this study is aimed to assess the effect of counseling for family planning at immunization units on postpartum contraceptive uptake during the extended postpartum period.

NCT ID: NCT04744155 Completed - Contraception Clinical Trials

Reducing Adolescent Pregnancy in the Emergency Department

Start date: May 12, 2021
Phase: N/A
Study type: Interventional

A multi-site randomized trial. Adolescents enrolled in this Clinical Trial will be enrolled into one of two arms. Adolescents in both arms will receive motivational interviewing enhanced counseling and a referral for follow up care. Those randomized in the Multi-level intervention arm will be offered immediate Emergency Department based contraception in addition to receiving a warm referral (providing help with scheduling follow-up care).