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Congestive Heart Failure clinical trials

View clinical trials related to Congestive Heart Failure.

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NCT ID: NCT00652652 Completed - Clinical trials for Congestive Heart Failure

Evaluation of Combined Action Between Natrecor and Furosemide on Kidney and Neurohormone Responses in Chronic Heart Failure: A Phase-IV study704.351 / DSS

Start date: March 2003
Phase: Phase 4
Study type: Interventional

This is a randomized, open-label, three-way crossover design study with 3 treatment groups:TREATMENT A: Furosemide;TREATMENT B: Nesiritide administered IV bolus, followed by an infusion for 6 hours;TREATMENT C: Treatment B for at least 15 minutes, then administration of treatment AAll sequences involving both furosemide and nesiritide had the nesiritide infusion started first, at least 15 minutes before furosemide was administered. Each treatment will be administered according to 1 of 6 sequences to which patients are randomized. Patients will remain in the Clinical Research Unit for 7 days, with treatments administered on Days 2, 4, and 6, with equilibrium (rest) days on Days 1, 3, and 5. All patients will be followed for safety throughout the treatment phase, and by telephone between 7 and 14 days after they are discharged from the Clinical Research Unit.

NCT ID: NCT00644410 Completed - Clinical trials for Congestive Heart Failure

Autologous Mesenchymal Stromal Cell Therapy in Heart Failure

Start date: September 2008
Phase: Phase 1/Phase 2
Study type: Interventional

It is a single centre, randomised controlled study of the effect of NOGA-guided direct intramyocardial injection of mesenchymal stromal cells on the development of new myocardium and blood vessels in patients with heart failure. Stem cells will be obtained from the bone marrow and culture expanded for 6 - 8 weeks before injected into the myocardium. The patients will be followed with safety, clinical, MRI and CT endpoints for 1 year.

NCT ID: NCT00634712 Completed - Clinical trials for Congestive Heart Failure

Candesartan Cilexetil in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Preserved)

Start date: June 1999
Phase: Phase 3
Study type: Interventional

A study to evaluate the effect of Atacand on patients with heart failure with preserved left ventricular function

NCT ID: NCT00634400 Completed - Clinical trials for Congestive Heart Failure

Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Alternative)

Start date: March 1999
Phase: Phase 3
Study type: Interventional

A study to evaluate the effect of Atacand on patients with heart failure with depressed left ventricular function

NCT ID: NCT00634309 Completed - Clinical trials for Congestive Heart Failure

Candesartan Cilexetil in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Added)

Start date: June 1999
Phase: Phase 3
Study type: Interventional

A study to evaluate the effect of Atacand on patients with heart failure with depressed left ventricular function

NCT ID: NCT00629538 Completed - Clinical trials for Congestive Heart Failure

Therapeutic Thoracentesis for Patients With Congestive Heart Failure and Large Pleural Effusion

Start date: March 2007
Phase: N/A
Study type: Interventional

Transudative pleural effusions are a common manifestation of patients with congestive heart failure. Severe dyspnea and respiratory failure may develop in those with large effusions, which in general show poor response to medical treatment. Therapeutic thoracenteses (TT) may be indicated in these patients and can produce marked relief of symptoms. However, the underlying effect of TT on gas exchange and respiratory mechanics in theses patients remains unclear. The researchers' hypothesis is that,TT may improve arterial oxygenation and respiratory mechanics in patients with congestive heart failure complicated by large pleural effusions.

NCT ID: NCT00627029 Active, not recruiting - Cancer Clinical Trials

Evaluation of Programs of Coordinated Care and Disease Management

Coca
Start date: September 2000
Phase: N/A
Study type: Interventional

This is a Congressionally mandated study. In the original study, 16 demonstration programs provided care coordination services to beneficiaries with chronic illness in Medicare's fee-for-service program. A five-year CMS-funded study tested whether the programs can improve patients' use of medical services, improve patients' outcomes and satisfaction with care, and reduce Medicare costs. The study also assessed physicians' satisfaction with the programs. In 2008 Congress extended the project for two of the original programs--Mercy Medical Center - North Iowa and Health Quality Partners in Pennsylvania--and they will enroll Medicare beneficiaries and provide care coordination services into the spring of 2010.

NCT ID: NCT00620048 Terminated - Clinical trials for Cardiovascular Disease

Stem Cell Study for Subjects With Congestive Heart Failure

Start date: March 2008
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if cell therapy with your own cells (autologous cells) delivered with a catheter to regions of the heart with poor blood flow will be safe and if it will improve your ejection fraction and heart failure symptoms.

NCT ID: NCT00611260 Completed - Clinical trials for Congestive Heart Failure

Improvement in Clinical Outcomes in Heart Failure Patients With ICDs That Practice Meditation

Start date: April 2007
Phase: N/A
Study type: Interventional

This is a trial to examine the effects of meditation on the incidence of ventricular arrhythmias and the psychological profiles in patients with implanted cardiac defibrillators. We wish to test the following hypotheses: 1. Vipassana meditation reduces the incidence of atrial and ventricular arrhythmias in patients with congestive heart failure. 2. Vipassana meditation improves the psychological profile in patients with CHF. In this study, subjects meeting the inclusion and exclusion criteria will be recruited into the study after obtaining informed consent. The subjects will then be randomized into either an experimental group ( Meditation) or into a control group (usual care).

NCT ID: NCT00603213 Completed - Clinical trials for Congestive Heart Failure

Correlation of Intrathoracic Impedance Measures With Blood Plasma Volume in Congestive Heart Failure

Optivol
Start date: January 2007
Phase: N/A
Study type: Observational

Congestive heart failure is a condition in which the heart is weakened and is unable to pump enough blood to the organs of the body to meet the demands of the body. At times there may be a buildup of fluid in the lungs, legs or other parts of the body. The accumulation of this fluid has been shown to affect the resistance to flow of the electrical impulses generated in the heart. The purpose of this study is to correlate measurements to the passive flow of electricity generated by the heart within the chest (as measured by the Optivol TFS System) with measurements of the volume of blood in the body.