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Congestive Heart Failure clinical trials

View clinical trials related to Congestive Heart Failure.

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NCT ID: NCT02686749 Terminated - Atrial Fibrillation Clinical Trials

Catheter Ablation vs. Medical Therapy in Congested Hearts With AF

CATCH-AF
Start date: June 2016
Phase: Phase 4
Study type: Interventional

This study is a multi-center, randomized, unblinded, clinical trial. The objective is to determine if catheter-based atrial fibrillation (AF) ablation is superior to medical treatment in patients with impaired left ventricular (LV) function who have been diagnosed with symptomatic AF within the past 12 months.

NCT ID: NCT02673892 Terminated - Clinical trials for Chronic Obstructive Pulmonary Disease

Patient Oriented Discharge Summary Impact Study

PODS
Start date: February 2016
Phase: N/A
Study type: Interventional

Improving the patient experience has become a major focus of quality improvement efforts in Ontario and in health systems worldwide. However, our existing knowledge base is relatively under-developed, particularly in how patients experience care as they transition from one care setting to another and the relationship between patient experience and clinical outcomes. The Patient Oriented Discharge Summary (PODS) is a discharge instruction tool created by patients, caregivers, health-care providers and design experts. It provides a written template for providers to engage patients and caregivers when reviewing important instructions on medications, activity and diet restrictions, follow-up appointments and worrisome symptoms warranting emergency care following admission to hospital. The PODS also uses plain and simple wording, large fonts, pictograms, and includes white space for patients to take notes and provides the option for translation of major headings into the most common spoken languages. The PODS impact study will study the impact of using the PODS versus usual discharge instructions on patient experience and health outcomes in a provincial-wide randomized study across acute care and rehabilitation hospitals.

NCT ID: NCT02375399 Terminated - Clinical trials for Congestive Heart Failure

New Echocardiographic Parameters for Prediction of Response to Cardiac Resynchronization Therapy

NEW-CRT
Start date: March 2015
Phase: N/A
Study type: Observational

Echocardiography parameters for cardiac dyssynchrony had no predictive value in current multicentric prospective studies concerning cardiac resynchronization therapy. Comprehensive echocardiography and new parameters as 2D and 3D strain, as well as 3D echo have been analyzed, but their definite value has not been proven yet.

NCT ID: NCT02205411 Terminated - Heart Failure Clinical Trials

Clinical Trial to Evaluate the the ReliantHeart HeartAssist 5® VAD System in Patients Awaiting Heart Transplantation

Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the safety and effectiveness of the ReliantHeart HeartAssist 5® VAD System in patients listed for heart transplantation and at risk of death from refractory end-stage heart failure.

NCT ID: NCT02152566 Terminated - Clinical trials for Congestive Heart Failure

Nasal High Flow Therapy for the Treatment of Respiratory Insufficiencies During Sleep

Start date: April 2014
Phase: N/A
Study type: Interventional

Respiratory insufficiencies during sleep can lead to reductions in the level of oxygen in the blood during the night, which has been shown to contribute to a range of morbidities. The purpose of this study is to assess the possibility that a nasal high flow therapy device may be able to treat respiratory insufficiencies, by stabilizing breathing and preventing reduction in blood oxygen. Heart failure patients will be screened at a heart failure clinic, and will be asked to undergo an overnight sleep study to determine is they exhibit respiratory insufficiencies during sleep. This sleep study may be completed in the sleep laboratory (attended polysomnography, PSG) or in-home (in-home polygraphy, PG). If they are diagnosed with respiratory insufficiencies, they will be asked to attend further overnight studies to see if treatment with nasal high flow therapy can be used to stabilize breathing.

NCT ID: NCT02121158 Terminated - Clinical trials for Coronary Artery Disease

Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the Elderly

I-70
Start date: August 7, 2015
Phase: N/A
Study type: Interventional

The overall aim of this trial is to study the safety and efficacy of ICD implantation as a primary prevention strategy of sudden cardiac death in patients 70 years and older. This study will assess the many competing factors involved with ICD implantation including 1) the impact on mortality, especially in the context of a declining rate of sudden death with advanced age, 2) the tolerability of the powerful therapeutic action of the device, and 3) the impact on quality of life.

NCT ID: NCT02107495 Terminated - Clinical trials for Congestive Heart Failure

Evaluation of the Samsung LABGEO IVD-A20 CHF Test in a Point-of-Care Setting

Start date: March 2014
Phase: N/A
Study type: Observational

To establish the performance characteristics of the Samsung LABGEO IVD-A20 CHF Test in intended use settings, by comparing test results of the A20 CHF Test with results obtained from an FDA-cleared comparator assay.

NCT ID: NCT01872234 Terminated - Clinical trials for Congestive Heart Failure

MADIT ASIA Cardiac Resynchronization Trial

MADIT-ASIA
Start date: February 2014
Phase: Phase 3
Study type: Interventional

The purpose of this trial or study is to determine if pacemaker therapy can be a beneficial alternative to conventional medical therapy in patients with a history of moderate heart failure. The investigators are looking to enroll approximately 180 people in this trial. Patients will be randomized in two groups. One group will be implanted with a pacemaker and will continue to receive conventional medical therapy as prescribed by their doctor. The second group will continue to receive conventional medical therapy as prescribed by their doctor and will not be implanted with a pacemaker. Clinical histories, physical exams, and external device testing will be collected both at the time of enrollment in the trial and during follow-up study visits. Patients who enter the study will be seen for study visits at 1 month, 3 and 6 months.

NCT ID: NCT01836809 Terminated - Clinical trials for Congestive Heart Failure

Nesiritide and Renal Function After the Total Artificial Heart

Start date: April 2013
Phase: Phase 4
Study type: Interventional

The prevalence of renal dysfunction after implantation of the artificial heart is high. The infusion of exogenous B-type natriuretic peptide (BNP) after implantation of the total artificial heart (TAH) improves renal function in a sustained manner. The renal protective and hormone-modulating effects of nesiritide may be enhanced with ventriculectomy compared to heart failure surgery that leaves the native myocardium intact. The goal of this project is to determine the renal protective effects of nesiritide after implantation of a mechanical device.

NCT ID: NCT01757067 Terminated - Clinical trials for Congestive Heart Failure

Early Elimination of Premature Ventricular Contractions in Heart Failure

EVAC-HF
Start date: January 2013
Phase: N/A
Study type: Interventional

Premature ventricular contractions (PVC) are a very common irregular heart beat (arrhythmias) even in patients without heart disease. Frequent PVCs are thought to occur in about 1-4% of the general population. Many patients with PVCs complain about skipping of their heart (palpitations), shortness of breath and feeling tired. In some patients PVCs may also result in weakening of the heart muscle (heart failure), which might be reversible with suppression of the PVCs.