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Congenital Abnormalities clinical trials

View clinical trials related to Congenital Abnormalities.

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NCT ID: NCT06009601 Completed - Spinal Deformity Clinical Trials

The Relationship Between Pectus Deformities and Spinal Pathologies

Start date: March 9, 2023
Phase:
Study type: Observational

Pectus deformities are common anterior chest wall pathologies. Pectus excavatum is the most common chest deformity with an incidence of 0.1-0.3%. Although the incidence of adolescent idiopathic scoliosis (AIS) is 0.2-3% in the community, some studies show that this rate rises to 17.61-25.58% when it is associated with pectus deformity. While the pectus excavatum rotates the heart to the left with its ribs and cartilages, it pushes the thoracic vertebra to the right side with the internal counterforce created by the heart, which has been shown to push the spine to the right with an asymmetric horizontal force in scoliosis patients with pectus deformity. Based on this, in study, investigators aimed to determine whether there is any relationship between pectus deformities and spinal pathologies, and if there is a relationship, with which pathology it is most common, whether the type of scoliosis seen in pectus deformities with a prominent scoliosis prevalence is a pectus-specific curve, and whether this curve seen in scoliosis is associated with pectus. To determine whether there is a footprint or not.

NCT ID: NCT05900843 Completed - Cerebral Palsy Clinical Trials

Weight Abnormalities With Diet and Exercise Frequency in Egyptian Children With Cerebral Palsy

Start date: November 15, 2022
Phase:
Study type: Observational

The goal of this study was to find prevalence and correlations of different weight abnormalities and risk of abdominal obesity in a random sample of Egyptian children suffering from cerebral palsy. This cross- sectional study hypothesize the prevalence of weight abnormalities and risk of abdominal obesity in addition to positive correlations between weight abnormalities and number of exercise hours and frequency of meals in a random sample of Egyptian children suffering from cerebral palsy RESEARCH QUESTION: 1. What is the prevalence of weight abnormalities and and risk of abdominal obesity in Egyptian children with cerebral palsy? 2. Does the weight abnormalities correlates with number of exercise hours or frequency of meals in children with cerebral palsy?

NCT ID: NCT05894941 Completed - Clinical trials for Musculoskeletal Deformity

Effects of Corrective Exercises and Postural Education on Forward Head Posture

Start date: May 12, 2023
Phase: N/A
Study type: Interventional

Forward head posture is one of the most common postural problems that we face today. Sitting for long periods in poor posture and the excessive use of electronic devices has become a high risk for this postural abnormality. The goal of this [interventional study] is to [provide the participants with simple and easy corrective exercises for this abnormal posture which they can do anywhere at any time and to provide postural education and awareness on the matter.

NCT ID: NCT05883761 Completed - Clinical trials for Congenital Abnormalities

Birth Outcomes In Eswatini After Transition To Dolutegravir-Based Treatment

Start date: September 7, 2021
Phase:
Study type: Observational

The goal of this observational study is to assess the birth outcomes of HIV-positive women delivering in hospitals in Eswatini who are receiving dolutegravir (DTG) or other anti-retroviral (ARV) drug regimens. The main question the study aims to answer is, what is the proportion of neural tube defects among live and stillborn infants delivered by: - HIV-positive women on DTG at conception - HIV-negative women - HIV-positive women on non-DTG ARV at conception Participants will be interviewed for information on HIV testing and antiretroviral therapy history, other medical history of selected conditions (e.g., diabetes, malaria, TB) and potential birth defect exposures. Photographs will be taken of the infants. Data on mothers' pregnancy history, birth outcomes, and HIV and ARV information (as applicable) will be collected from patient records.

NCT ID: NCT05879094 Completed - Healthy Subjects Clinical Trials

Orthopaedic Simulation of Morton's Extension to Test the Effect on Plantar Pressures of Each Metatarsal Head in Patients Without Deformity: A Pre-post-test Study.

Start date: May 29, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to simulate the orthopedic treatment called Morton's extension on non-deformed patients to check the effects on each metatarsal head on its static footprint.

NCT ID: NCT05848388 Completed - Clinical trials for Paediatric Dentistry

Molar Incisor Malformation in Egypt

Start date: May 30, 2022
Phase:
Study type: Observational

The aim of the current study is to assess the prevalence of molar incisor malformation in Fayoum-Egypt.

NCT ID: NCT05821803 Completed - Clinical trials for Foot; Pronation, Congenital

The Effect of Exercise Training and Arch Supported Insoles on Balance and Vertical Jump Performance in Football Players With Foot Pronation Deformity

Start date: May 13, 2022
Phase: N/A
Study type: Interventional

This study aims to investigate the effects of foot pronation exercises and arch support insoles on balance and vertical jump test in football players.

NCT ID: NCT05817084 Completed - ACL Injury Clinical Trials

Patients With Acl Injury and Varus Knee Will Undergo Acl Reconstruction Alone, or Combined With High Tibial Osteotomy in the Same Session.

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the results of single-stage anterior cruciate ligament reconstruction combined with high tibial osteotomy and anterior cruciate ligament reconstruction alone in knees with varus malalignment and anterior cruciate ligament deficiency. Evaluation will be clinically, radiologically and time needed to return to pre injury activity level. Our Hypothesis: Simultaneous anterior cruciate ligament reconstruction and high tibial osteotomy provides good functional scores, low rate of graft failure and early return to pre injury activity level with minimal added morbidity.

NCT ID: NCT05813938 Completed - Clinical trials for Abnormalities in the Blood Test Results

Assessment of Accuracy and Safety of LabTest Checker

LTC-AI
Start date: December 22, 2022
Phase: N/A
Study type: Interventional

The goal of this study is to assess performance of a new clinical decision support system named LabTest Checker in a cohort of adult patients reporting to the internal ward's emergency department. The main question it aims to answer is: • how accurate and safe is LabTest Checker. A set of blood laboratory tests will be ordered for each participant. Participants will use LabTest Checker to obtain an interpretation of their test results. The interpretation provided by LabTest Checker will then be compared with the interpretation given by an internal medicine specialist to assess the accuracy and safety of the tool.

NCT ID: NCT05810545 Completed - Preeclampsia Clinical Trials

Drinking Water PFAS, Pregnancy Outcome and Maternal Morbidity

Start date: January 1, 2012
Phase:
Study type: Observational [Patient Registry]

The aim of the project is to assess the association between exposure to per- and polyfluoroalkyl substances (PFAS) via drinking water in pregnancy and birth outcomes (i.e. growth retardation, premature birth, and congenital developmental defects) and maternal morbidity (gestational hypertension, diabetes and preeclampsia) in a prospective population-wide register study.