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Colonoscopy clinical trials

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NCT ID: NCT02647229 Withdrawn - Colonoscopy Clinical Trials

Colonic Irrigation for Colonoscopy Preparation

Start date: October 2014
Phase: N/A
Study type: Interventional

The purpose of this physician blinded, randomized study is to determine the utility, effectiveness, and feasibility of using colonic irrigation as a substitute for standard oral colonic purgative solutions for colonoscopy preparation. Patients will be randomized to receive either oral isosmotic solution (PEG) or colonic irrigation using the Hydro San Plus Colon therapy system, an FDA approved and isosmotic (ISO) certified device for colonic irrigation and cleansing before endoscopic procedures.

NCT ID: NCT02643316 Completed - Colonoscopy Clinical Trials

Morning-Only 4 L PEG vs Split Dose Prep for Afternoon Colonoscopies, Endoscopist-Blinded Prospective Study

Start date: December 2015
Phase: N/A
Study type: Interventional

Comparison of quality of preparation of colonoscopy in patients taking same day 4L preparation vs. 4 L split dose preparation in patients scheduled for an afternoon colonoscopy procedure.

NCT ID: NCT02563132 Completed - Colonoscopy Clinical Trials

Carbon Dioxide Insufflation Colonoscopy in IBD Patients

Start date: October 2015
Phase: N/A
Study type: Interventional

Carbon dioxide insufflation during colonoscopy significantly reduces discomfort (pain, bloating and flatulence) after the procedure. So far, it has not been studied in inflammatory bowel disease patients. The study was designed to evaluate discomfort after the carbon dioxide insufflation colonoscopy in comparison to standard air insufflation colonoscopy.

NCT ID: NCT02532647 Completed - Colonoscopy Clinical Trials

Safety and Efficacy of Remimazolam in ASA III and IV Patients Undergoing Colonoscopy

Start date: November 2015
Phase: Phase 3
Study type: Interventional

A prospective, double-blind, randomized, placebo and active controlled, multi-center, parallel group study comparing remimazolam to placebo, with an additional open-label arm for midazolam, in American Society of Anesthesiologists (ASA) Grade III and IV patients (ASA status evaluated by an anesthesiologist not otherwise involved in the study) undergoing a colonoscopy for diagnostic or therapeutic reasons.

NCT ID: NCT02484105 Recruiting - Colonoscopy Clinical Trials

Comforting Conversation During Colonoscopy: A Trial on Patient Satisfaction

ComConEndo
Start date: September 2015
Phase: Phase 4
Study type: Interventional

Does comforting conversation during colonoscopy improve on patient satisfaction, compliance and pain management.

NCT ID: NCT02407925 Completed - Colonoscopy Clinical Trials

Implementation of Optical Diagnosis for Diminutive Polyps Amongst Endoscopists: Training and Long-term Quality Assurance

DISCOUNT2
Start date: January 1, 2015
Phase: N/A
Study type: Observational

In this study, Dutch gastroenterologists who are certified for performing colonoscopies on FIT-positive patients in the Dutch population screening program are trained in optical diagnosis with validated methods. After this training, an ex- and in-vivo test phase leads to "accreditation" and endoscopists will be observed in their optical diagnosis for 1 year. During this year, half of the endoscopists will be randomized towards 3-monthly feedback and the other half will receive feedback on their results after 1 year. The endoscopic prediction of endoscopists on polyp histology will be compared to histopathological outcome.

NCT ID: NCT02407639 Completed - Colonoscopy Clinical Trials

Insufflation in Children Undergoing Colonoscopy

Start date: March 2015
Phase: Phase 4
Study type: Interventional

Studies in adults have shown that post-procedural abdominal pain is reduced with the use of CO2 instead of air for insufflation during colonoscopy. The aim of our study is to compare post-procedural abdominal pain and girth in children undergoing colonoscopy using CO2 or air for insufflation.

NCT ID: NCT02310139 Completed - Colonoscopy Clinical Trials

Failed/Difficult Colonoscopy Outcomes

FoDCO
Start date: May 2015
Phase:
Study type: Observational

Colonoscopy is a commonly used investigation to diagnose and treat various gastrointestinal disorders. In addition, colonoscopy provides the opportunity to remove colonic adenomas this removal is also known as polypectomy. Polypectomy has proven to reduce occurrence of colorectal cancer and likelihood of dying from it. Colonoscopy can be challenging due to technical or patient factors. In a small proportion of patients a complete colonoscopy is unsuccessful. Such patients either get referred to a tertiary centre with extensive experience in difficult colonoscopy or have an alternative test such as CT scan. The investigators unit has accumulated significant experience related to previously failed colonoscopy and anecdotally appears to have a high success rate in completing the procedure. The purpose of this project is to describe the investigators technical approach to management of patients with previously failed colonoscopy. There is no additional intervention and the project is observational in nature. The investigators will collect data on patient characteristics, the reason for the failure and what technique was used to overcome the difficulty. The investigators will also note whether the final outcome of the technique had any impact on the overall management of the patient.

NCT ID: NCT02305706 Completed - Colonoscopy Clinical Trials

Right or Left for Colonoscopy?

ROLCOL
Start date: April 2014
Phase: N/A
Study type: Interventional

Colonoscopy is technically challenging. Conventionally, colonoscopy begins with patients positioned in the left lateral position. However, few published studies have explored alternatives and there is consequently little evidence to support left lateral starting position over alternatives.

NCT ID: NCT02290873 Completed - Colonoscopy Clinical Trials

A Phase III Study of the Efficacy and Safety of Remimazolam Compared to Placebo and Midazolam in Colonoscopy Patients

Start date: March 30, 2015
Phase: Phase 3
Study type: Interventional

A prospective, double-blind, randomized, placebo and active controlled, multi-center, parallel group study comparing remimazolam to placebo, with an additional open-label arm for midazolam, in patients undergoing a colonoscopy for diagnostic or therapeutic reasons.