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Colonoscopy clinical trials

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NCT ID: NCT00975247 Completed - Colon Cancer Clinical Trials

Impact of a Novel Patient Educational Booklet on Colonoscopy Quality

Start date: April 2008
Phase: N/A
Study type: Interventional

Background: Achievement of colonoscopy outcomes depends on high-quality bowel preparation by patients; yet inadequate preparation is common. Objective: To develop and test an educational booklet to improve bowel preparation quality. Design: "Before-and-after" study followed by randomized controlled trial. Setting: Veteran Affairs medical center. Patients: Patients undergoing outpatient colonoscopy Measurements: The investigators first performed cognitive interviews to identify knowledge and belief barriers to high-quality colonoscopy preparation. The investigators then created a patient educational booklet addressing patient barriers to improve preparatory behaviors. The investigators tested the booklet in 2 sequential studies: (1) controlled "before-and-after" study in patients undergoing colonoscopy during 2 consecutive months: 1 without and 1 with the booklet; (2) randomized controlled trial. The outcome in both studies was bowel preparation quality measured on a 6-point Likert scale (>5="good"). In each study the investigators compared the proportion achieving a "good" preparation between groups and performed logistic regression to measure the effect of the booklet on preparation quality while adjusting for the purgative received. Limitations: Unknown impact on polyp yield and cancer reduction.

NCT ID: NCT00953017 Completed - Colonoscopy Clinical Trials

A Trial Comparing Split-Dose Miralax With Amitiza Pretreatment Versus Dulcolax Pretreatment Versus Golytely for Bowel Cleansing Prior to Colonoscopy

Start date: July 2009
Phase: Phase 4
Study type: Interventional

Miralax (PEG 3350) has been shown to be a safe and uncomplicated bowel preparation prior to colonoscopy in pediatric populations. This study seeks to confirm the efficacy of this bowel cleansing regimen in adults and to determine the benefit of adding a pretreatment medication to this bowel preparation. The tolerability of Miralax will hopefully improve patient satisfaction with colonoscopy and decrease their reluctance to be screened because of the uncomfortable taste and side effects of bowel preparation regimens.

NCT ID: NCT00930462 Completed - Colonoscopy Clinical Trials

Evaluation of the Use of Cap in Improving the Performance of Colonoscopy

Start date: March 2008
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare the colonoscopy success rate, cecal time and polyp detection rate between cap-fitted colonoscopy and conventional colonoscopy.

NCT ID: NCT00929916 Completed - Colonoscopy Clinical Trials

Comparing Two Different Ways to Take MoviPrep® Before Colonoscopy

Start date: December 2008
Phase: N/A
Study type: Observational

This study will evaluate whether morning-only dosing of MoviPrep® (2L) for afternoon colonoscopy is as effective as a standard dosing regimen of half of the volume of MoviPrep® (1L) solution the evening prior, and half (1L) the morning of, colonoscopy. MoviPrep® is a low volume (2 liters) polyethylene glycol (PEG)-based purgative that is approved for evening-only or split (evening and morning) dosing to cleanse the colon prior to colonoscopy. Patients undergoing afternoon colonoscopies often have inferior colon cleansing. There is evidence that morning-only purgative administration of large volume PEG (4L) is safe and effective. This study will assess whether administration of a low volume PEG regimen will maintain efficacy and improve tolerance by changing a 2-day preparation procedure into a regimen that is completed in 1 day.

NCT ID: NCT00908648 Completed - Colonoscopy Clinical Trials

The Use of Narrow Band Imaging in Screening Colonoscopy

Start date: November 2007
Phase: N/A
Study type: Interventional

Narrow band imaging (NBI) is an imaging technique that allows a better definition of capillary pattern and improves the contrast between adenomas and the surrounding mucosa. Conflicting data exist on the ability of NBI in to improve detection of colonic neoplasm; the impact of NBI is being tested in several screening scenarios. The investigators evaluated whether the routine use of NBI, compared to white light (WL), during the withdrawal phase of screening colonoscopy improved adenoma detection.

NCT ID: NCT00905554 Completed - Colonoscopy Clinical Trials

Warm Water for Unsedated Colonoscopy

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Start date: April 2009
Phase: N/A
Study type: Interventional

Unsedated colonoscopy is characterized by lower costs, recovery time and incidence of drug-related side effects, although it may be painful for the patient. Based on recent reports, the investigators designed this randomized controlled trial hypothesizing that the use of water irrigation versus air insufflation during the insertion phase of colonoscopy might increase the global tolerability of the examination and the proportion of patients undergoing complete colonoscopy without sedation.

NCT ID: NCT00885274 Completed - Colonoscopy Clinical Trials

A Randomized Controlled Trial Comparing Two Timing Regimens of Pico-salax for Colon Cleansing Prior to Colonoscopy

Start date: November 2008
Phase: Phase 4
Study type: Interventional

Pico-Salax is an osmotic and stimulant bowel cleansing agent used prior to colonoscopy. It is unknown whether splitting the doses (i.e. taking the second dose the morning of the colonoscopy) results in a better bowel cleansing, as research with other agents suggests this may be the case. This study aims to assess whether splitting the dose of Pico-Salax results in a better bowel cleansing than traditional dosing.

NCT ID: NCT00883545 Completed - Colonoscopy Clinical Trials

Study of Adherence to Colonoscopy in Women

Start date: October 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether women who are offered screening colonoscopy will be more likely to schedule and complete this procedure if they are given the option of a woman endoscopist.

NCT ID: NCT00868920 Completed - Colonoscopy Clinical Trials

Patient-Controlled Sedation Versus Anesthesiologist-Administered Sedation

Start date: January 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to see whether patients controlling their own sedation during colonoscopy are less likely to need help breathing than when an anesthesiologist controls the medicine, and whether we can predict when the need for help will occur. The pump used in the study is approved for clinical use by the FDA, as are the medicines used in the pump.

NCT ID: NCT00857272 Completed - Colonoscopy Clinical Trials

F38-27: An Evaluation of 2 Different Bowel Cleansing Preparations in Adult Subjects

Start date: February 2009
Phase: Phase 4
Study type: Interventional

To compare the safety and efficacy of 2 different bowel cleansing preparations prior to colonoscopy in adult subjects.