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NCT ID: NCT06134609 Recruiting - Embryo Transfer Clinical Trials

Does Sexual Intercourse Affect the Outcomes of Frozen-thawed Embryo Transfer?

Start date: November 13, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test whether sexual intercourse the night after embryo transfer affects thawed embryo implantation rates. Women undergoing one of their first four frozen embryo transfers with a good quality embryo will be randomly assigned to two groups. The study group is subjected to have intercourse without using a condom at the evening/night after the embryo transfer, while the control group will abstain from intercourse for the next 48 hours after the transfer. Researchers will compare the ongoing pregnancy rates between the intervention group and the control group.

NCT ID: NCT02306655 Unknown status - Quality of Life Clinical Trials

Coital Incontinence: Incidence and Quality of Life Impact.

Start date: October 2014
Phase: N/A
Study type: Observational

Fundamentals of scientific research The "coital incontinence" (IC), defined as the "involuntary loss of urine in association with sexual intercourse." The incidence reported in the literature ranges from 10% to 27%, but is likely to be underestimated because of the embarrassment of the woman to report the disturbance. It was in fact estimated that only 3% of women speaks spontaneously to their doctor, and increases up to 20% only after a request by the medical staff. The CI is traditionally divided into two forms: 1. incontinence at the time of penetration (60% of cases) 2. incontinence during orgasm (40% of cases) Many theories have been proposed to justify this form of urinary incontinence, but none has been conclusively proved .Moreover, it has not been possible, to date, to identify risk factors, anatomical or urodynamics, for this condition. The IC is rarely a symptom isolated, but more frequently associated with other forms of urinary incontinence. In particular, the IC during penetration of associated with stress urinary incontinence (loss of urine that occurs due to coughing, sneezing and in general to all those activities that increase abdominal pressure); the IC during orgasm is associated more frequently to a condition of overactive bladder (presence of urgency, urge incontinence, increased urination day and night). The IC has a strong impact on female sexuality and can cause loss of libido, non orgasmic, decreased sexual satisfaction and, in some cases, termination of sexual activity. Research goals Evaluate a prospective investigation of health statistics, the incidence of coital incontinence into consideration that there are few data in the literature on this disorder and those who have reported a wide variance probably connected to how the data collection. The aim is to be able to identify a "threatening condition" which, if not evaluated, worsens the prognosis of the treatment of female urinary incontinence, a condition that has a negative impact on the quality of life of patients with significantly worse than that related to other recognized debilitating chronic diseases such as diabetes. And this individual psychosocial cost, hardly quantifiable, must be added the cost of significant socio-economic and welfare dependents of incontinent patients, the community and national health services. It is indeed evident from international and national literature that the more incisive and determined is the strategy of information, awareness and education, and adopted much wider and earlier the diagnosis, the more significant is the socio-economic savings, as well as psycho social, we get. Ultimate goal is to differentiate between them the two forms of incontinence coital (to penetration and during orgasm) because each of them is associated with pathogenesis and therefore to a separate treatment. And while the forms of IC penetration favorably affected the treatment of stress urinary incontinence, the forms of IC during orgasm, usually associated with a functional disorder of the detrusor (detrusor overactivity) show an inferior efficacy to treatment antimuscarinic traditionally reserved to the condition of overactive bladder and therefore need a more targeted diagnostic and individualized treatments. Materials and methods Self administered questionnaires will be dispensed to the patients The questionnaires,validated in Italian language, will be used, according to the guidelines of the International Consultation on Incontinence, : - ICIQ-UI on urinary incontinence short-form: for the evaluation of symptoms and quality of life: - Patient Perception of Bladder Condition (PPBC): to assess the impact of such a subjective condition; - Urinary incontinence and quality of sexuality; - Urinary incontinence and frequency of sexual activity; The questionnaire is anonymous in order to protect privacy. The patients will be recruited at the outpatient surgery and Urogynaecology urodynamics of Urology Clinic of the University of Perugia. The investigators defined that the statistically significant number of subjects can not be less than 200 units. The time duration of the collection of medical records was estimated at two years. There are no extremes of the conflict of interest, will not be tested or used drugs or medical equipment.

NCT ID: NCT00779025 Completed - Coitus Clinical Trials

A Safety Evaluation of Personal Lubricant Product When Used by Couples in Home-use Conditions

Start date: January 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to study in couples and to evaluate the safety of personal lubricant products.

NCT ID: NCT00778934 Completed - Coitus Clinical Trials

In-Home Use Study to Evaluate Use of an Intimate Health Product in Females

Start date: December 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effects of an intimate health product on sexual experience in females.