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Cognition clinical trials

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NCT ID: NCT06412315 Not yet recruiting - Depression Clinical Trials

7T Amygdala and Citalopram Study

7TAC
Start date: July 2024
Phase: N/A
Study type: Interventional

The goal of this study is to investigate how a common antidepressant citalopram (which increases the levels of the chemical messenger serotonin), affects how a key area of the brain involved in depression (the amygdala) responds to emotional information. Healthy participants will undergo medical and psychiatric health screening, after which they will be assigned to receive either a single dose of citalopram (20mg) or placebo, and undergo brain scanning (7T fMRI) whilst viewing emotional faces. Since the scan uses high field strength, the investigators will be able to see effects of citalopram on different subfields within the amygdala which will help to understand how citalopram might be working.

NCT ID: NCT06408415 Not yet recruiting - Cognition Clinical Trials

A Study of the Higher Cognitive Functions of the Human Brain With Single-neuron Activity Recording

Start date: May 2024
Phase:
Study type: Observational

This study aims to investigate that neural activity of higher cognitve function of human brain with hyperflexible neural electrode-cortex

NCT ID: NCT06340282 Not yet recruiting - Cognition Clinical Trials

Immersive Virtual Reality and Physical Exercise on Cognitive and Functional Performance in Hospitalized Older Patients

MOTOMED
Start date: April 1, 2024
Phase: N/A
Study type: Interventional

This study will be conducted in a hospital in Spain to investigate how a special intervention using immersive virtual reality technology can benefit hospitalized older adults with difficulties in their daily functionality. The main objective of this study is to evaluate whether a cognitive stimulation intervention through immersive virtual reality, along with specific physical exercises, can improve the cognitive and physical function of hospitalized older patients. It is expected that this innovative intervention will have a positive impact on the quality of life of these patients. Participants eligible for the study must be over 75 years old, have severe functional dependency upon hospital admission, and be willing to participate. Those with severe dementia or other terminal illnesses will be excluded. Participants will be randomly assigned to one of four study groups: a control group without intervention and three intervention groups, including viewing Spanish landscapes through virtual reality, performing specific physical exercises, or a combination of both interventions. At the end of the study, various aspects such as cognitive and physical function, mood, quality of life, muscle strength, and acceptance of virtual reality technology by patients will be evaluated. This study aims to provide new insights into the care of hospitalized older adults and explore innovative ways to improve their well-being during their hospital stay

NCT ID: NCT06229262 Not yet recruiting - Cognition Clinical Trials

Immune and Cognitive Benefits of Mango Intake in Young Adults

Start date: June 2024
Phase: N/A
Study type: Interventional

The main objectives of our proposed study are to determine the effects of mango consumption on immune and cognitive functions in free-living college going young adults aged 18-30 years

NCT ID: NCT05930288 Not yet recruiting - Exercise Clinical Trials

The Effect of Preoperative Walking Exercises on the Prognosis of Supratentorial Brain Tumours Patients After Craniotomy

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about in patients with supratentorial brain tumours. The main questions it aims to answer is: Can short-term preoperative walking exercise protect cognitive function in the short term after craniotomy in patients with supratentorial brain tumor and reduce the incidence of surgery-related complications? Participants will be asked to receive general care and regular walking exercises prior to surgery. Researchers will compare patients who receive only general care before surgery to see if preoperative walking exercise has an effect on postoperative prognosis.

NCT ID: NCT03781557 Not yet recruiting - Cognition Clinical Trials

Effects of Omega-3 Fatty Acids Supplement in Cognition of Young Healthy Adults and in Their Reaction Time of Computerized Test After 3 Months of Taking High-concentrated DHA and EPA Fish Softgels

Start date: January 1, 2019
Phase: Phase 4
Study type: Interventional

In this trial, the investigators are going to investigate the improvement of cognitive brain domains after ingestion of omega 3 products that have high concentrations of DHA, Docosahexaenoic acid, and EPA, Eicosapentaenoic acid, in comparison to control group young healthy adults. The study will assess the improvement by computerized testing by their reaction time before and after the intervention. The researchers will follow the scientific and ethical regulations prevent any harmful effect on recruited subjects.

NCT ID: NCT03619291 Not yet recruiting - Exercise Clinical Trials

High-intensity Functional Circuit Training and Cognitive Function

Start date: August 2018
Phase: N/A
Study type: Interventional

The study investigates the acute effects of one bout of high-intensity functional circuit training on cognitive function against no-activity control and aerobic exercise.

NCT ID: NCT02133664 Not yet recruiting - Multiple Sclerosis Clinical Trials

Lipoic Acid and Omega-3 Fatty Acids for Cognitive Impairment in Multiple Sclerosis

Start date: June 2014
Phase: Phase 1/Phase 2
Study type: Interventional

The primary aim is to collect data to determine the correct effect size on the primary outcome to aid in the design of a larger study: The primary outcome is to determine if lipoic acid and omega-3 fatty acids can improve cognitive function in people with multiple sclerosis that have cognitive dysfunction.