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Cognition clinical trials

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NCT ID: NCT05107947 Suspended - Inflammation Clinical Trials

Light in Frail Elderly - the Effect of a Dynamic Light for Sleep and Circadian Rhythm

LIFE
Start date: October 31, 2022
Phase: N/A
Study type: Interventional

The aim of this project is to evaluate the effect of a dynamic light in order to improve the circadian rhythm, provide a better sleep and well-being, and in the long run an improved recovery. The primary question is whether dynamic artificial light with circadian stimulus can affect the circadian rhythm. The secondary question is whether this also provides better sleep and well-being. The group that is particularly interesting to study is a geriatric population that is more sensitive to circadian rhythm disorders, sleep disorders and confusion in connection with hospitalization and that can be of particular benefit from this intervention.

NCT ID: NCT01212029 Suspended - Cognition Clinical Trials

Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging

Start date: September 8, 2011
Phase: N/A
Study type: Interventional

Background: - Non-invasive functional near infrared (fNIR) imaging techniques use infrared light to detect changes in blood volume and oxygen levels during brain activity. fNIR is being studied as a possible way to examine the brain activity of individuals who are unable to undergo standard brain function imaging techniques (such as functional magnetic resonance imaging, or fMRI). For instance, war veterans who have iron shrapnel in the body are not able to have fMRI scans, and very young children or children with autism and related disorders are often not able or willing to cooperate long enough in the MRI environment to allow full imaging studies to take place. Researchers are interested in comparing the results of fNIR and fMRI performed on healthy volunteers to determine if fNIR produces similarly accurate results. Objectives: - To examine the capabilities of non-invasive functional near infrared imaging techniques on healthy volunteers and compare the results with the existing outcomes of functional magnetic resonance imaging. Eligibility: - Healthy volunteers at least 18 years of age. Design: - Participants will have one study visit. Depending on the complexity of the task, the whole exam will take between 5 minutes and 1 hour to perform. - Participants will be asked to sit as still as possible while wearing a headband that includes light sources and detectors (the fNIR device). - Participants will be asked to perform a set of tasks (e.g., reading sentences or counting numbers in one s head). Data will be collected during these experiments.