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Cognition clinical trials

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NCT ID: NCT00968851 Completed - Schizophrenia Clinical Trials

Safety and Cognitive Function Study of EVP-6124 in Patients With Schizophrenia

Start date: December 2009
Phase: Phase 2
Study type: Interventional

This study is being conducted to determine the safety and effect on cognitive function of two different doses of an investigational medication, EVP-6124, in individuals with schizophrenia who are on chronic stable atypical anti-psychotic therapy. In addition, behavioral and psychotic symptoms will be evaluated.

NCT ID: NCT00924300 Completed - Cognition Clinical Trials

Study to Test the Usefulness of Magnetoencephalography (MEG) Imaging of Cognition in Children and Adolescents

Start date: July 15, 2009
Phase:
Study type: Observational

The primary objective of this protocol is to test the feasibility and utility of obtaining magnetoencephalography (MEG) recordings in healthy children and also in children who have a psychiatric or developmental disorder. Secondary objectives are to examine and compare typical and atypical motor, sensory, and cognitive functioning as recorded by MEG, and to identify subpopulation groups for which MEG may be optimal in order to establish feasibility of future hypothesis-driven MEG research.

NCT ID: NCT00879203 Completed - Cognition Clinical Trials

Glycemic Control, Brain Structure and Cognition in Youth With Type 1 Diabetes (T1DM)

LO5/HY5
Start date: November 2008
Phase: N/A
Study type: Observational

LO5 study: The investigators are inviting a new group of youth (ages 7-16) who have been recently diagnosed with type 1 diabetes and their non-diabetic siblings. These youth will complete cognitive tests and a MRI scan of the brain. This scan uses strong magnets to obtain pictures and does not involve any radiation or injections. The investigators will recruit patients within three months of their diagnosis date. The study entails 1 study visit that lasts 3.5 hours. Evening and weekend times are available. The investigators plan to enroll 135 participants. HY5 study: The investigators are inviting a cohort of youth and young adults (ages 9-21) with type 1 diabetes and their non-diabetic siblings for a follow-up to a study they have already completed. This group of people will complete several memory and thinking tests along with several MRI scans of their brain, just as they did at their previous visits. The investigators plan to enroll 150 participants.

NCT ID: NCT00846950 Completed - Cognition Clinical Trials

Effects of H1-Antagonist on Cognition

Start date: December 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether histamine is involved in memory and specific processes in human cognition.

NCT ID: NCT00830986 Completed - Cognition Clinical Trials

Cognition Following Computer Assisted Total Knee Arthroplasty

Minimental
Start date: July 2005
Phase: N/A
Study type: Observational

A significant number of patients experience postoperative cognitive changes following total joint arthroplasty. Among other causes, the mental status change may be the result of fat and bone marrow debris embolization. We hypothesized that the use of computer assisted total knee arthroplasty, which does not utilize intramedullary alignment rods, would produce less fat and bone marrow debris embolization and, hence, fewer mental status changes.

NCT ID: NCT00810667 Completed - Schizophrenia Clinical Trials

Efficacy Study Exploring the Effect of Lu AE58054 as Augmentation Therapy in Patients With Schizophrenia

Start date: November 2008
Phase: Phase 2
Study type: Interventional

The objective of this study is to explore the efficacy, safety and cognitive properties of Lu AE58054 as augmentation therapy to risperidone in patients with schizophrenia.

NCT ID: NCT00782938 Completed - Cognition Clinical Trials

The Role of Serum Anticholinergic Activity in ACVB Patients

Start date: May 2008
Phase: N/A
Study type: Observational

Drugs with anticholinergic potential increase the risk of postoperative transient and persistent cognitive dysfunction especially in cardiac patients. The investigators main goal is to identify preoperative risk factors and to monitor postoperative patients' state in relation to SAA activity and bilateral BIS-EEG changes.

NCT ID: NCT00741143 Completed - Clinical trials for Iron Deficiency Anemia

Effect of Iron Fortified Wheat Flour on Cognition and Iron Status in Indian School Children

Start date: August 2007
Phase: N/A
Study type: Interventional

This study is designed to evaluate the efficacy of NaFeEDTA-fortified whole wheat flour in improving cognition, hemoglobin, iron status and total body iron among school children in urban Bangalore.

NCT ID: NCT00687102 Completed - Aging Clinical Trials

Cognition in the Study of Tamoxifen and Raloxifene

Co-STAR
Start date: October 2001
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the effects of tamoxifen and raloxifene on cognitive aging in selected cognitively-healthy women.

NCT ID: NCT00654706 Completed - Schizophrenia Clinical Trials

Efficacy Study Exploring the Effects on Cognition of Sertindole Versus Comparator in Patients With Schizophrenia

Start date: March 2008
Phase: Phase 3
Study type: Interventional

The objective of this study is to explore the neurocognitive efficacy of Sertindole versus comparator in patients with schizophrenia using the MCCB.