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Cicatrization clinical trials

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NCT ID: NCT06114394 Not yet recruiting - Cicatrization Clinical Trials

Complications Related to Palatal Graft Harvesting

Start date: October 30, 2023
Phase: N/A
Study type: Interventional

Soft tissue defects can be a problem, especially in patients with high smile lines; in these clinical scenarios, the treatment with periodontal plastic surgery in combination with the use of a connective tissue graft (CTG) is considered the gold-standard procedure. Single incision technique (Huerzeler & Weng, 1999) is one of the suggested procedures to harvest the CTG from palate. The UPV/EHU technique (Aguirre-Zorzano et al, 2017) showed less inflammation and post-surgical complications than trap-door technique, but also other technique should to be analysed. However, there is still no consensus about which is the best technique to obtain this kind of graft. Therefore, clinicians should justify their choice based on the tissue's quality obtained and the patient's well-being, producing the least number of complications, such as inflammation, post-surgical pain, or recession in the donor area. HYPOTHESIS: Does the technique of obtaining an CTG of the palate using the "UPV/EHU technique" (Aguirre-Zorzano et al., 2017) result in a lower number of complications versus the "single incision technique" (Huerzeler & Weng, 1999)? OBJECTIVES The main objective is to assess whether the complications occurring with the harvesting of the CTG using the "UPV/EHU technique" (Aguirre-Zorzano et al., 2017) are lower than with the "single incision technique"(Huerzeler & Weng, 1999), knowing the patient's perception of pain. The secondary objectives are: a) necrosis of the palate, b) possible resulting recession in the donor area, and c) characteristics of the graft obtained

NCT ID: NCT04168125 Recruiting - Pain, Postoperative Clinical Trials

Use of Tilapia Skin for Palate Repair and Protection After Graft Removal

Start date: September 26, 2019
Phase: Phase 1
Study type: Interventional

Randomised Clinical Study to evaluate the efficacy of tilapia skin as an occlusive biological dressing on palatal wound healing after free gingival graft harvesting.

NCT ID: NCT03188913 Not yet recruiting - Burns Clinical Trials

Factor XIII in Major Burns Coagulation

Start date: June 19, 2017
Phase: N/A
Study type: Observational

Prospective observational study in which FXIII levels and coagulation tests and cicatrization are measured during the 30 days after the thermal trauma.

NCT ID: NCT01410175 Completed - Wound Infection Clinical Trials

Comparison of the Impact of Electric Scalpels Versus Cold Scalpels

SCL01
Start date: July 2010
Phase: Phase 3
Study type: Interventional

Surgical site infection (SSI) is the second commonest hospital infection, despite advances in prevention that have been achieved. According to Fernàndes, experimental studies have demonstrated that incorrect use of electric scalpels may double the rate of SSI during electrocauterization. Because of the lack of solid data in the literature, in relation to the impact on SSI of using electric scalpels for making incisions in the skin and all subcutaneous tissues, it was judged to be opportune to conduct the present study. Objectives: - To compare the incidence of SSI and other complications of the operative wound among patients undergoing elective abdominal gynecological surgery at Barretos Cancer Hospital, between the use of electric and cold scalpels. - To identify the incidence of SSI and other complications of the operative wound among patients undergoing elective abdominal gynecological surgery, when using electric scalpels for skin incisions and for subcutaneous incisions. - To identify the main risk factors for SSI among patients undergoing elective abdominal gynecological surgery.