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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05611476
Other study ID # CMT-LBP-6581
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date December 8, 2022
Est. completion date August 1, 2023

Study information

Verified date November 2023
Source University of Salford
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The primary aim of this study is to adapt Cognitive Muscular Therapy so that it can be used to manage chronic low back pain. A secondary aim is to understand the potential therapeutic benefit of this intervention.


Description:

There is evidence that people with chronic low back pain (LBP) demonstrate muscle overactivity during functional tasks when compared to healthy controls. Interestingly, this increased activity of the low back and trun, muscles has been associated with increased sensitivity to pain. It has also been shown that people with chronic LBP exhibit alterations in functional movement patterns and postures when compared to healthy people. Such alterations may be a direct result of increased stiffness in the spine which results from muscle overactivity. Psychosocial physiotherapy techniques for LBP are gaining widescale acceptance. However, these approaches are often combined with strengthening exercises, and not specifically aimed at reducing muscle overactivity. Therefore, there is a need for research into interventions for chronic LBP which integrate psychologically informed practice with training to reduce muscle overactivity. The investigators have developed a new treatment for people with knee osteoarthritis, known as Cognitive Muscular Therapy (CMT). CMT is a form of psychologically informed physiotherapy which uses biofeedback training to reduce muscle overactivity and therefore lower the mechanical stress on the knee. CMT is delivered through five sequential intervention components and teaches patients to think and respond differently to pain, to improve postural control and to perform functional movements, such as walking, with less muscle tension. See the dedicated website for further details (https://hub.salford.ac.uk/cognitive-muscular-therapy/). Given the strong focus on postural control, the investigators are confident that CMT can be adapted and used to treat other chronic musculoskeletal conditions, such as LBP. In this project, the investigators will map changes to the five CMT intervention components. The intervention will then be delivered to patients with chronic low back pain, after which the investigators will seek to understand participant perceptions of the new treatment.


Recruitment information / eligibility

Status Completed
Enrollment 15
Est. completion date August 1, 2023
Est. primary completion date July 1, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: 1. Above 18 years old 2. Speak and understand English sufficient to read the information sheet and sign the consent form 3. Ability to walk without an assistive device for at least 100m (to ensure patients have sufficient mobility to be able to complete the intervention) 4. Low back pain for at least three months' duration 5. Currently scoring 4 or more on the Roland disability scale Exclusion Criteria: 1. Dementia or other major cognitive impairment 2. Red flags (specific causes of LBP, such as acute disc prolapse with radicular pain, or other serious pathology) 3. Pregnancy 4. History of serious spinal injury (fractures, spinal cord injury) 5. BMI >33 (as EMG measurement is not possible in people with higher BMI) 6. Acute low back pain (Onset less than 3 months) 7. Any systemic inflammatory disorders, such as rheumatoid arthritis 8. Any balance disorders which may increase the risk of a fall

Study Design


Related Conditions & MeSH terms


Intervention

Behavioral:
Cognitive Muscular Therapy for low back pain
Psychologically informed physiotherapy which used biofeedback training to reduce muscle overactivity and improve postural control

Locations

Country Name City State
United Kingdom University of Salford Manchester Greater Manchester

Sponsors (1)

Lead Sponsor Collaborator
University of Salford

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type Measure Description Time frame Safety issue
Primary Change in Rowland Morris Disability questionnaire Used to capture pain/disability associated with low back pain. Score 0-24 (0=no pain, 24=maximum pain) Change from baseline to 2 months
Secondary Change in Pain catastrophizing scale Used to capture pain catastrophizing behaviours. Score 0-52 (0=no pain catastrophizing, 52=maximum pain catastrophizing) Change from baseline to 2 months
Secondary Change in Tampa scale of kinesiophobia Used to capture kinesiophobia behaviours. Score 17-68 (0=no kinesiophobia, 52=maximum kinesiophobia) Change from baseline to 2 months
Secondary Change in Oswestry disability scale Used to capture intensity of low back pain. Score 0-100 (0=no pain) Change from baseline to 2 months
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