Radiofrequency Splanchnic Denervation Versus Retrocrural Neurolytic Celiac Block for Pancreatic Cancer Pain

Chronic Pain Clinical Trial

Official title:

For Patients With Pancreatic Cancer Pain, Does Radiofrequency Splanchnic Denervation Isprovide a Similar Analgesia as Neurolytic Celiac Block

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03886298
• Other study ID #: SECI-IRB-IORG0009563-725
• Status: Recruiting
• Phase: N/A
• Start date: April 10, 2019
• Est. completion date: June 10, 2020

Study information

• Verified date: July 2019
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The investigators will evaluate the analgesic efficacy of radiofrequency splanchnic nerve denervation versus neurolytic retrocrural celiac denervation for patients with abdominal pain due to cancer pancreas

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: June 10, 2020
• Est. primary completion date: April 10, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 16 Years to 90 Years

Eligibility

Inclusion Criteria:

• patients with abdominal pain due to cancer pancreas

Exclusion Criteria:

• coagulopathy

• infection at site of the procedure

Related Conditions & MeSH terms

• Cancer Pain
• Chronic Pain
• Pancreatic Neoplasms

Intervention

Procedure:
• radiofrequency splanchnic denervation
the authors will denervate the splanchnic nerves via radiofrequency
• retrocrural celiac denervation
the authors will denervate the splanchnic nerves in the retrocrural space via injection of alcohol

Locations

Country	Name	City	State
Egypt	Diab	Assiut	Assuit

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the percentage of patients that gain more than 50% reduction of their pain on VAS pain score	VAS pain scale is a tool for measurement of pain intensity scored from 0 to 10 in which 0 + no pain and 10 + the worst pain immaginable	6 months postoperatively