Chronic Cough Clinical Trial
Official title:
The Use of Capsaicin Challenge for Diagnosis, Monitoring and Follow-up of Chronic Cough.
The purpose of this study is to determine whether the capsaicin challenge can improve the diagnosis, treatment, monitoring and follow-up in patients with chronic cough.
Capsaicin is administrated in incremental concentrations with two inhalations of normal saline solution. Patients are instructed to exhale to functional residual capacity and than to inhale through the mouthpiece for 1 second (single breath inhalation). The number of coughs in the first 10 seconds after each inhalation is counted. C2; the concentration of which the patient responded by 2 coughs, C5;the concentration of which the patient responded by 5 coughs. The challenge ends at C5. ;
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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