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Cesarean Section Complications clinical trials

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NCT ID: NCT04812522 Completed - Clinical trials for Cesarean Section Complications

Clean-CS: A Program to Improve the Safety of C-section

Clean-CS
Start date: August 26, 2021
Phase: N/A
Study type: Interventional

Executive summary: Cesarean delivery, or section (CS), is the single most common surgical procedure performed. Estimates indicate that in low resource settings, CS comprises up to 50% of more of the total volume of operations performed. The World Health Organization recommends national CS rates of between 10-15% to save lives and improve maternal and neonatal outcomes. Population-based work indicates that CS rates of up to 19% are demonstrably related to improved maternal and neonatal survival. However, complications are common, and gynecological and obstetric surgical interventions are associated with high rates of morbidity. In low resource settings, complication rates are particularly high. The intervention being tested is based on a previously developed program called Clean Cut. Clean Cut is an adaptive, multimodal surgical infection prevention program that integrates perioperative process improvement and patient outcomes measurement using process mapping, training and improved management practices, and compliance with critical standards of surgical antisepsis. It was successfully piloted in five surgical departments in Ethiopia, and reduced the relative risk of infection by 35%. This has been adapted specifically for obstetric and gynecological operations and will be evaluated in a cluster randomized stepped wedge trial design in ten maternity hospitals/departments in Ethiopia in order to reduce infections and other complications for women undergoing cesarean delivery and other obstetric and gynecologic operations.

NCT ID: NCT04766567 Completed - Clinical trials for Cesarean Section Complications

Complications in Singleton Pregnancies Following Previous Cesarean Myomectomy

Start date: June 15, 2020
Phase: N/A
Study type: Interventional

The present study aims to investigate whether there is a difference in short- and long-term complications in patients undergoing cesarean myomectomy (endometrial or serosal myomectomy) during cesarean section.

NCT ID: NCT04752904 Completed - Hypotension Clinical Trials

Noninvasive Continuous Blood Pressure Monitoring for Cesarean Delivery

Start date: April 27, 2021
Phase: N/A
Study type: Interventional

Noninvasive continuous blood pressure monitoring for preventing post-spinal hypotension during cesarean delivery: A randomized controlled trial

NCT ID: NCT04734366 Completed - Clinical trials for Cesarean Section Complications

Effect of Baseball Suturing on Isthmocele and Residual Myometrial Thickness After Cesarean

Start date: December 17, 2020
Phase: N/A
Study type: Interventional

Cesarean delivery rates in Turkey as well as all over the world are increasing. Recent data in Turkey shows that the value of cesarean delivery rate reached 53%. This worldwide increase causes new concerns. Incomplete healing of the uterine scar after cesarean is a complication with potential long-term consequences. There is evidence that the risk of uterine scar defects is associated with the number of previous cesarean deliveries and the method of uterotomy closure. Study was designed as prospective randomized clinical trial to analyze the effects of two different uterine suture techniques. The investigators aim is to compare the closure of the incision with the "baseball" suture technique and the single-layer locking technique in terms of the incidence and depth of the isthmocele in the uterine incision scar as a short-term result.

NCT ID: NCT04733313 Completed - Postoperative Pain Clinical Trials

Effect of Quadratus Lumborum Block in C/S

Start date: July 15, 2017
Phase: N/A
Study type: Interventional

to compare postoperative analgesic effects of USG guided QLB-2 and QLB-3 blocks after C/S. We hypothesized that QLB-3 may be more effective for pain relieving than QLB-2 after C/S.

NCT ID: NCT04711317 Completed - Anesthesia Clinical Trials

Pre-oxygenation With High-flow Nasal Cannula in Caesarian Section Under General Anesthesia

PRIOROB
Start date: March 3, 2021
Phase: N/A
Study type: Interventional

The investigators and other groups have demonstrated that high-flow nasal oxygen used during preoxygenation for emergency surgery is at least equally effective as preoxygenation compared to standard tight fitting mask. The investigators also have data from a recent study that indicates that high-flow nasal oxygen might decrease the risk of clinically relevant desaturation below 93% of arterial oxygen saturation. The studies investigating the concept of high-flow nasal oxygen has up to this date excluded pregnant women. Pregnant woman is a patient group with known difficulties to maintain adequate saturation levels during apnoea. Due to smaller functional residual capacity their oxygen stores after preoxygenation are smaller compared to patients with a normal body mass index. The pregnant woman also have a higher oxygen demand and metabolism due to the growing placenta and the fetus. Pregnant women are therefore a patient group where a method that could prolong time until desaturation would be even more valuable and potentially could save lives. Based on the above, the investigators now aim to conduct a clinical pilot study, where pregnant women undergoing caesarian section under general anesthesia are pre and perioxygenated with high-flow nasal oxygen. Data from that group will be compared with patients preoxygenated in a traditional manner with tight facemask. This study is done to evaluate an established technique on a patient category that in theory could gain a lot from it.

NCT ID: NCT04685980 Completed - Clinical trials for Cesarean Section Complications

Factors Associated With Failed Spinal Anesthesia for Cesarean Delivery

Start date: December 25, 2020
Phase:
Study type: Observational

The aim of this study is to reveal the factor associated with failed spinal anaesthesia in cesarean delivery. We conduct the retrospective case-control study to elucidate the involving factors.

NCT ID: NCT04657692 Completed - Obesity, Morbid Clinical Trials

Incidence of Complications Associated With Anesthesia in Obesity Parturient Undergoing Cesarean Delivery

Start date: December 29, 2020
Phase:
Study type: Observational

The incidence of obesity parturient has been increasing worldwide. There was a report revealing one third of pregnant women in United state considered obesity. Obesity is associated with increased in maternal and neonatal complications. Also, there was an increasing in the rate of cesarean delivery. Anesthetic management of the obese parturient is differ from non-obese parturients. There were higher risk of difficult intubation, failed intubation, pulmonary aspiration and difficult regional anesthesia such as spinal anesthesia or epidural catheter placement comparing with non-obese parturient. The aim of the study is to report complication associated with anesthesia in obese patients undergoing cesarean delivery in Single University hospital, Bangkok, THAILAND.

NCT ID: NCT04635007 Completed - Clinical trials for Cesarean Section Complications

Tranexamic Acid Versus Misoprostol in Reducing Blood Loss in Cesarean Section in Primigravida

Start date: January 1, 2021
Phase: Phase 3
Study type: Interventional

The aim of the work is to compare the efficacy of preoperative IV tranexamic acid and rectal misoprostol in reducing blood loss in the elective cesarean section. Research question: In women undergoing elective cesarean section, is preoperative administration of IV tranexamic acid better than rectal misoprostol in reducing blood loss?

NCT ID: NCT04612998 Completed - Obesity Clinical Trials

Combined Spinal Epidural Anesthesia in Obese Patients Undergoing Cesarean Surgery

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

This study investigated the maternal and fetal effects during performance of CSEA in the left lateral decubitus and sitting positions in obese pregnant women undergoing elective cesarean section.