Cerebrovascular Accident Clinical Trial
Official title:
Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of Speech
Impaired speech production is a major obstacle to full participation in life roles by stroke survivors with aphasia and apraxia of speech. The proposed study will demonstrate the short-term effects of auditory masking on speech disfluencies and identify individual factors that predict a positive response, enabling future work to develop auditory masking as a treatment adjuvant targeting long-term improvement in speech. Providing an additional treatment option for adults with aphasia and apraxia of speech will have the clear benefit of improving quality of life and allowing individuals to participate more actively in their health care decisions through improved communication.
Status | Recruiting |
Enrollment | 45 |
Est. completion date | December 2015 |
Est. primary completion date | December 2015 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria for Aphasic/Apraxic Participants: - Single left-hemisphere cerebrovascular accident - Speech errors are present, but participant is able to produce approximations of words or sentences by reading or repetition; < 90% and > 10% on Chapel Hill Multilingual Intelligibility Test (Haley, 2011) - Right-handed prior to stroke by report - Normal visual attention, acuity, and color vision - Pure-tone threshold <= 40 decibels in at least one ear Exclusion Criteria for Aphasic/Apraxic Participants: - Predominating disorders of cognition or hearing (e.g. dementia, hearing impairment). - Presence of degenerative neurological illness (e.g. Parkinson's disease, amyotrophic lateral sclerosis, primary progressive aphasia). Inclusion Criteria for Neurologically Healthy Participants: - Matched in age and sex to a participant with aphasia - score of 90% or higher on the single-word intelligibility test - Right-handed prior to stroke by report - Normal visual attention, acuity, and color vision - Pure-tone threshold <= 40 decibels in at least one ear Exclusion Criteria for Neurologically Healthy Participants: - History of stroke - History of developmental speech or language disorder |
Observational Model: Case Control, Time Perspective: Cross-Sectional
Country | Name | City | State |
---|---|---|---|
United States | University of North Carolina School of Medicine | Chapel Hill | North Carolina |
Lead Sponsor | Collaborator |
---|---|
University of North Carolina, Chapel Hill | National Institute on Deafness and Other Communication Disorders (NIDCD) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Disfluency duration change with masking noise | Measured disfluency duration in sentences produced while listening to masking noise compared to speaking in quiet without noise. | 1 day of the study | No |
Secondary | Speech rate change with masking noise | Measured syllables per second in sentences produced while listening to masking noise compared to speaking in quiet without noise. | 1 day of the study | No |
Secondary | Speech sound accuracy change with masking noise | Measured speech sound accuracy in sentences produced while listening to masking noise compared to speaking in quiet without noise. | 1 day of the study | No |
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