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Cataract clinical trials

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NCT ID: NCT05265832 Completed - Cataract Clinical Trials

Influencing Factors of the Corneal Endothelial Cell Loss

PREDICS
Start date: May 4, 2022
Phase: N/A
Study type: Interventional

This is a multi-center cohort study with prognostic aims to identify factors associated with endothelial cell loss during cataract surgery. Patients will have their endothelial density measured by specular microscopy preoperatively, at 1 month and at 3 months after surgery. The rest of their management will be in line with standard practice.

NCT ID: NCT05262504 Completed - Quality of Life Clinical Trials

Comparison of a Novel Non-diffractive Extended Depth of Focus Intraocular Lens (IOL) and a Trifocal IOL

Start date: April 1, 2021
Phase:
Study type: Observational

The purpose of this study is to compare visual performance and quality of life (QOL) following bilateral implantation of a novel non-diffractive extended depth-of-focus (EDOF) intraocular lens (IOL) (AcrySof® IQ Vivity, Alcon, TX, USA) and a trifocal IOL (Acrysof® IQ PanOptix, Alcon, Fort Worth, TX) in a prospective comparative interventional case series.

NCT ID: NCT05262205 Completed - Ophthalmic Clinical Trials

Bispectral Index Monitoring In Pediatric Cataract Surgery: A Comparative Study Using Propofol-Midazolam Versus Sevoflurane Anesthesia

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

Ocular alignment will be studied in children having cataract surgery that will be divided into two groups, one group will be anesthetized using sevoflurane anesthesia (group A), and the other will be anesthetized by midazolam bolus and propofol infusion (total intravenous anesthesia, TIVA) (group B). in both groups depth of anesthesia will be monitored by bispectral index monitor.

NCT ID: NCT05260775 Completed - Cataract Clinical Trials

Intelligent Evaluation and Supervision of Cataract Surgery

Start date: January 1, 2019
Phase:
Study type: Observational

Research purpose: intelligent identification and evaluation of cataract surgery steps Research methods: A total of 9 items (such as gender, age, visual acuity, etc.) were extracted from the surgical videos of senile cataract patients and the clinical data recorded by the electronic medical record system. The machine learning algorithm 3D-CNN was applied to identify the 11 steps in cataract surgery and the pictures (blank pictures) without instrument manipulation on the eyeball during the operation. Six key cataract surgery steps were scored using deep learning algorithms (probability smoothing window and softmax). We employ precision, precision, recall, and F1-score to evaluate the model's performance for recognizing surgical steps. To evaluate the reliability of the model's scoring of surgical steps, we used a human-machine comparison method to calculate the agreement (kappa value) between machine and expert scores.

NCT ID: NCT05255029 Completed - Cataract Clinical Trials

Clinical Investigation of a Monofocal Toric Intra Ocular Lens (IOL) in Cataractous Eyes

PHY2107
Start date: December 24, 2021
Phase: N/A
Study type: Interventional

This is a Multi-center, single-arm and non-masked study whereby patients undergoing routine cataract surgery be implanted with a hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC (model POD T 49P).

NCT ID: NCT05254587 Completed - Cataract Clinical Trials

Accuracy of IOLMASTER 700 Total Keratometry (TK)

Start date: February 8, 2022
Phase:
Study type: Observational

This is a multicenter study to compare the accuracy of IOL calculations in post-laser vision corrected eyes that are about to undergo or have undergone cataract surgery.

NCT ID: NCT05249413 Completed - Cataract Clinical Trials

Early Vitrectomy for Endophthalmitis After Cataract Surgery

Start date: January 2, 2015
Phase:
Study type: Observational

Post-operative infectious endophthalmitis is devastating condition that causes a diffuse intraocular inflammation and may lead to blindness. Acute post-operative endophthalmitis usually presented within 6 weeks of intraocular procedure and diagnosis is confirmed by clinical examination and by the aid of B-scan ultrasonography.

NCT ID: NCT05242653 Completed - Cataract Clinical Trials

Comparison of Wound Integrity for Clear Corneal Cataract Incisions

Start date: February 17, 2022
Phase: N/A
Study type: Interventional

This is a randomized controlled trial to evaluate the safety and efficacy of two different closing methods for clear corneal cataract incisions

NCT ID: NCT05239715 Completed - Clinical trials for Optical Biometer, Cataracts

Evaluation of Three SS-OCT and One PCI Optical Biometers in Eyes With Dense Cataract

BIO-CAT-DENSA
Start date: February 10, 2022
Phase:
Study type: Observational

To describe and compare the acquisition rate between different biometers in eyes with advanced cataracts

NCT ID: NCT05235139 Completed - Cataract Clinical Trials

PMCF Study on Comparison of EDOF Lenses (Switzerland)

PHY2130
Start date: March 9, 2022
Phase: N/A
Study type: Interventional

Single center, prospective, randomised, controlled, double-blind post-market clinical follow-up (PMCF) study to compare the clinical outcomes of a premium monofocal intraocular lens (PhysIOL ISOPURE 1.2.3.) with clinical data obtained in a control group implanted with an EDOF IOL (Alcon Acrysof IQ Vivity).