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Cataract clinical trials

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NCT ID: NCT05372315 Completed - Cataract Clinical Trials

Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surgery With PCIOL.

DEXTENZA
Start date: June 15, 2022
Phase: Phase 4
Study type: Interventional

To assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) with or without iStent/Hydrus/Goniotomy when placed in the lower punctum compared to the upper punctum.

NCT ID: NCT05364658 Completed - Cataract Clinical Trials

A Clinical Evaluation of the LensGen Intraocular Lens

Grail
Start date: November 18, 2018
Phase: N/A
Study type: Interventional

A multi-center, open-label, non-comparative clinical trial to assess the safety and efficacy of the LensGen IOL (Juvene IOL) for the treatment of aphakia and presbyopia after removal of the natural crystalline lens due to cataract.

NCT ID: NCT05359380 Completed - Cataract Clinical Trials

The Impact of Light Conditions on the Efficacy of Multifocal Intraocular Lens Implantation in Activities of Daily Living

Start date: September 15, 2021
Phase:
Study type: Observational [Patient Registry]

Primary objective of this study is to identify the optimal task lighting conditions (in terms of light intensity and light temperature) for 10 activities of daily living (ADLs) that require near or intermediate vision acuity in a validated ADL simulation framework for a sample of patients who underwent presbyopic correction with bilateral multifocal intraocular lenses (IOLs) implantation, and to compare their capacity to perform ADLs (ADL scores) between three study groups (SG): SG1. patients implanted bilaterally with trifocal diffractive IOLs, SG2. patients implanted bilaterally with bifocal hybrid (diffractive-refractive) IOLs, SG3. patients implanted bilaterally with monofocal IOLs

NCT ID: NCT05347615 Completed - Cataract Senile Clinical Trials

Achieving Hybrid Monovision By Paring Monofocal And EDOF Lens Technology

Start date: October 10, 2019
Phase:
Study type: Observational

Modern day cataract surgery isn't just a rehabilitative procedure anymore but rather aims at improving a patient's quality of life by reducing the need for spectacles in everyday life to a minimum. One way of achieving this goal is by using different lens technologies, such as a monofocal lens paired a lens with EDOF technology, as EDOF lenses provide an enhanced depth of focus by creating a single elongated focal point. As this "mix-and-match" is well established, the aim of this study is to compare the monofocal lens cohort to the EDOF lens cohort and evaluate visual acuity and patient satisfaction.

NCT ID: NCT05346172 Completed - Cataract Clinical Trials

The Clareon PanOptix Trifocal IOL: Visual Outcomes and Patient Satisfaction

Start date: June 17, 2022
Phase:
Study type: Observational

This will be a single arm, open-label, prospective study of patient-reported outcomes of patients with bilateral implantation of the Panoptix or Panoptix Toric implant.

NCT ID: NCT05335408 Completed - Visual Acuity Clinical Trials

Evaluation of Visual Function After Bilateral Implantation of EDOF IOLs

Vario-NL
Start date: May 2, 2022
Phase: N/A
Study type: Interventional

Since intermediate vision is becoming increasingly important in our day-to-day tasks, a new IOL was introduced (Acunex Vario) with this objective in mind. This IOL provides excellent vision at far and intermediate distances up to 60 cm and with negligible photopic disturbances compared to conventional multifocal lenses. The Alcon AcrySof IQ Vivity IOL is designed to provide continuous vision from distance to intermediate while preserving contrast sensitivity and with a monofocal visual disturbance profile. So far, there are no published studies comparing these new IOL designs that offer an extended range of vision at far and intermediate distances. Objective: The primary objective of this study is to compare the binocular uncorrected intermediate visual acuity (UIVA) at 66 cm under photopic conditions 3 months postoperatively, in a series of patients bilaterally implanted with the Vario IOL versus those bilaterally implanted with the Vivity IOL. Study design: controlled double masked, randomized, prospective clinical trial Study population: patients of 18 years or older with bilateral cataracts that require cataract surgery. Intervention: One group receives bilateral implantation with the Vario IOL and the other group receives bilateral implantation with the Vivity IOL. Main study parameters: The main study parameter is the binocular UIVA at 66 cm under photopic conditions at 3 months postoperatively. Hypothesis: The investigators hypothesise that bilateral implantation with the Vario IOL is non-inferior when compared to bilateral implantation with the Vivity IOL, with regards to binocular UIVA at 66 cm under photopic conditions 3 months postoperatively. Cataract extraction in this study will proceed according to regular cataract surgery. As with any type of intraocular surgery, there is a possibility of complications due to anesthesia, drug reactions, and surgical problems. Postoperatively, there will be one extra postoperative visit, compared to standard cataract surgery follow-up. Spectacle-independency postoperatively, without photopic phenomena, is one of the major expected benefits when treating cataract (and presbyopia) with the implantation of the Vario or Vivity IOLs.

NCT ID: NCT05323526 Completed - Cataract Clinical Trials

Validation of the Catquest-9SF Questionnaire in Greek Language

Start date: February 15, 2020
Phase:
Study type: Observational [Patient Registry]

Primary objective of this study is the validation of the Catquest-9SF questionnaire in the Greek population.

NCT ID: NCT05287269 Completed - Clinical trials for Age Related Macular Degeneration

Ocular Coherence Tomography During Cataract Assessment

Start date: November 2, 2020
Phase:
Study type: Observational [Patient Registry]

Many patients will have underlying maculopathy present when undergoing cataract surgery, which are not visible on fundoscopy alone. Knowledge of this underlying pathology will allow an improved consenting process and discussion with the patient regarding the risks, visual prognosis and recovery following cataract surgery. Incidental findings in the fellow eye would also allow for improved diagnosis and management of these patients without adding significant additional time to specialist high volume cataract assessment clinics.

NCT ID: NCT05278936 Completed - Congenital Cataract Clinical Trials

New Technique in Congenital/Pediatric Cataract Surgery

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

In pediatric/congenital cataract surgery; multiple surgical interventions are performed, which needs multiple general anesthesias. Here, we describe a new technique, to end the operation in one session.

NCT ID: NCT05278442 Completed - Cataract Clinical Trials

Evaluation of the Accuracy & Safety of the LaserArcs Nomogram

Start date: April 1, 2022
Phase:
Study type: Observational

Evaluation of the Accuracy and Safety of the LaserArcs Femtosecond Cataract Surgery Arcuate Incision Nomogram in Patients Undergoing Cataract Surgery and Astigmatism Reduction