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Cataract clinical trials

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NCT ID: NCT03016156 Recruiting - Retinoblastoma Clinical Trials

Determination of the Sensitivity and Specificity of a Smartphone Application to Detect Retinoblastoma

Start date: March 15, 2018
Phase: N/A
Study type: Interventional

This study seeks to determine whether a smartphone application called CRADLE (ComputeR Assisted Detection of LEukocoria) has the potential to improve the detection of leukocoria. There will be no impact on participants' health outcome. This study will be performed in two parts, each with a distinct cohort of patients. Part 1 will assess the feasibility of various techniques/conditions for using CRADLE within patients known to have leukocoria. Part 2 will estimate the sensitivity and specificity of CRADLE to detect leukocoria (using the techniques selected from information gathered in Part 1) as compared to an ophthalmoscope, within patients referred to the clinic for suspected leukocoria. PRIMARY OBJECTIVES: - To determine the most effective usage of a camera phone application (CRADLE) to maximize detection of leukocoria in patients with retinoblastoma, congenital cataracts, and glaucoma. - To estimate the sensitivity and specificity of a camera phone application (CRADLE) in detecting leukocoria.

NCT ID: NCT02908633 Recruiting - Clinical trials for Primary Open Angle Glaucoma, Cataract

Safety and Efficacy of Three Variants of Canaloplasty With Phacoemulsification to Treat Glaucoma and Cataract

Start date: February 2016
Phase: N/A
Study type: Interventional

It is a comparative study of Safety and Efficacy of Three Variants of Canaloplasty: ab-externo, ab-interno and minicanaloplasty. Combined With Phacoemulsification to Treat Glaucoma and Cataract. It is a Randomised, Prospective Study.

NCT ID: NCT02863159 Recruiting - Cataract Clinical Trials

A Clinical Assessment of the Full Range of Functional Vision With Three Tecnis Multifocal IOL 1-Piece Models in Bilateral Cataract Extraction

Start date: August 2015
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the uncorrected binocular distance, intermediate, and near visual acuities, and assess patient's spectacle independence and satisfaction in individuals undergoing bilateral cataract extraction that have received two different arms of near add design IOLs of the same diffractive multifocal model.

NCT ID: NCT02843594 Recruiting - Cataract Clinical Trials

A Study to Assess the Clinical Outcomes of Surgical Phaco Segmentation Techniques in Patients Undergoing Cataract Surgery

Start date: August 2016
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to evaluate the clinical outcomes of different cataract surgical techniques for lens fragmentation in subjects undergoing routine cataract surgery.

NCT ID: NCT02817191 Recruiting - Clinical trials for Age-related Cataract

Effects of Holy-Comod and Tears Naturale Forte in Patients After Phaco+IOL

Start date: June 2016
Phase: N/A
Study type: Interventional

The purpose of the study it to compare the effects of Holy-Comod and Tears Naturale Forte on ocular surface and tear inflammatory mediators in patients after Phaco+IOL.

NCT ID: NCT02678962 Recruiting - Cataract Clinical Trials

Comparison of Outcomes With Multifocal Intraocular Lenses

COMIL
Start date: February 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to compare and evaluate the clinical outcomes of 6 kinds of Multifocal Intraocular Lenses: SN6AD1, SBL-3, LS-313 MF30, AT LISA tri 839 MP, ART, LS-313 MF30T.

NCT ID: NCT02658071 Recruiting - Cataract Clinical Trials

Measurement of Ocular Tensional Fluctuation by Triggerfish Lens Before and After Cataract Surgery in Patients With Exfoliative Glaucoma

TRIGGERFISH
Start date: March 15, 2016
Phase: N/A
Study type: Observational

Glaucoma is a very frequent disease in Brittany. In glaucoma the retinal ganglion cells and their axons slowly die with visible changes at the optic nerve head (cupping). Without early diagnosis and effective treatment or with delayed treatment decrease of visual acuity or blindness become. In secondary pseudoexfoliation glaucoma grayish-white deposits of abnormal proteins are found on all surfaces of eye irrigated by the aqueous humor. The deposits of PEX material inside the trabecular meshwork decrease aqueous humour outflow and the intraocular pression raise. The exfoliation material is found on the surface of the lens capsule with frequent developement of nuclear cataract . After cataract surgery the intra ocular pressure (IOP) decrease. Some recent study have found decreasing ocular volume variation associated to IOP fluctuation in night after cataract surgery in normal pressure glaucoma patients. In our study we want see if it's the same thing in pseudoexfoliation glaucoma patients.

NCT ID: NCT02644720 Recruiting - Cataract Clinical Trials

Neural Compensation, Visual Function and Visual Quality After Monofocal or Multifocal Intraocular Lens Implantation

Start date: January 2014
Phase: N/A
Study type: Interventional

Multifocal intraocular lenses (MIOLs) provide enhanced far and near visual acuity, but they can bring about halos and glare, which are caused by design deficiencies of the IOLs. Compared to monofocal intraocular lens, pseudo accommodation in nonphysiological state may increase the difficulty of neural compensation reconstruction in patients with multifocal intraocular lens implantation. Patients enrolled into the study will be followed for 1 year and will have study visits preoperatively, at 1 week, 3 months, 6 months, 12 months postoperatively.In this trial, we aimed to specify the time of neural compensation reconstruction in patients and to explore the changes of visual function in senile patients with monofocal or multifocal intraocular lens implantation.

NCT ID: NCT02638220 Recruiting - Clinical trials for Cerebrotendinous Xanthomatosis (CTX)

Cerebrotendinous Xanthomatosis (CTX) Prevalence Study

Start date: September 2015
Phase:
Study type: Observational

This is an observational, multicenter study to determine the prevalence of Cerebrotendinous Xanthomatosis (CTX) in patient populations diagnosed with early-onset idiopathic bilateral cataracts. Patients who are potentially eligible for study participation will be identified through a chart review of patients who were seen at each study site prior to that site's initiation, or by entering care at the site while the site is participating in the trial.

NCT ID: NCT02590744 Recruiting - Anesthesia Clinical Trials

Effects of Preoperative Using of Eye Patches on Prevention of Emergence Agitation After Cataract Surgery

Start date: October 2015
Phase: N/A
Study type: Interventional

This study is a single-center, prospective, randomized, controlled trial. To investigate if preoperative using of eye patch will decrease emergence agitation, and to provide a better method of decreasing emergence agitation to pediatric ophthalmic anesthesiologists.