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Cataract clinical trials

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NCT ID: NCT02523950 Recruiting - Cataract Clinical Trials

Staged and Combined Surgery for Cataract Patients With Corneal Endothelial Dysfunction

Start date: March 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of staged and combined phacoemulsification with intraocular lens implantation and Descemet membrane endothelial keratoplasty (DMEK) to treat cataract patients with corneal endothelial dysfunction. Surgical and postoperative complications, visual acuity and corneal endothelial cell density are evaluated.

NCT ID: NCT02495220 Recruiting - Postoperative Pain Clinical Trials

Efficacy of Dexmedetomidine for Postoperative Analgesia in Infantile Cataract Surgery

Start date: July 2015
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of the present study was to evaluate the efficacy and safety of subtenon block (SB)anesthesia with dexmedetomidine in combination with bupivacaine versus intravenous dexmedetomidine for postoperative analgesia and emesis control in infants undergoing cataract surgery.

NCT ID: NCT02445274 Recruiting - Cataract Clinical Trials

Two Different Cataract Surgical Procedures to Prevent Posterior Capsule Opacification

Start date: May 2015
Phase: N/A
Study type: Interventional

In this study, the investigators introduce a new "capsule-reserved" cataract surgical procedure in which anterior lens capsule is reserved and attached onto posterior lens capsule in the purpose of preventing posterior capsule opacification (PCO). A prospective randomized controlled study is reported to compare the new "capsule-reserved" surgical procedure with conventional one on the effectiveness to prevent posterior capsule opacification in age-related cataract patients.

NCT ID: NCT02363530 Recruiting - Cataract Clinical Trials

Corneal Protect Used During Cataract Surgery

CPUDCS
Start date: November 2014
Phase: N/A
Study type: Interventional

This randomized controlled subject- and examiner-masked study comprised patients scheduled for cataract surgery.The patients will be randomly assigned to receive either balanced salt solution(BSS)or hydroxypropyl methylcellulose(HPMC)2% gel (Cornea Protect).Each subject should undertake examination including - rupture time (TBUT), height of the river of tears, fluorescence staining, Schirmer Ⅰ test, ocular surface disease index (OSDI) and self-conscious symptom assessment questionnaire for assessment.

NCT ID: NCT02362334 Recruiting - Cataract Clinical Trials

IOL Power Calculation Using Dual Schiempflug Analyzer

Start date: October 2014
Phase: N/A
Study type: Observational

This study evaluates the various ocular parameters which are necessary for ocular biometry and the calculated IOL powers using both dual Schiempflug analyzer and optical low-coherence refelctometry.

NCT ID: NCT02332369 Recruiting - Cataract Extraction Clinical Trials

EyeKon Medical Inc. Capsular Tension Ring Study

CTR
Start date: February 2005
Phase: N/A
Study type: Interventional

This study evaluates the safety and effectiveness of a capsular tension ring (CTR) when used during cataract surgery. Capsular Tension Rings are used during intraocular lens implantation to give added support in order to keep the intraocular lens well centered, especially in eyes with weak or partially absent zonules. In many cases, capsular tension rings allow a lens to be successfully implanted into an eye which otherwise could not have supported an intraocular lens.

NCT ID: NCT02312362 Recruiting - Cataract Clinical Trials

High Frequency Deep Sclerotomy (HFDS) ab Interno a Combination Surgical Intervention Using Cataract Surgery to Lower IOP

HFDS_abinterno
Start date: November 2012
Phase: N/A
Study type: Interventional

Objective: To compare intraocular pressure lowering effect of combined sclerotomy ab interno with phacoemulsification and phacoemulsification alone, in primary or secondary open angle glaucoma patients. Study design: Prospective, randomized, case- control interventional surgical trial

NCT ID: NCT02277314 Recruiting - Cataracts Clinical Trials

Manual Small Incision Cataract Surgery Outcomes in an Educational Setting

MSICS
Start date: April 2014
Phase: N/A
Study type: Interventional

The overall objective is to determine the visual outcomes and cost to perform Manual Small Incision Cataract Surgery (MSICS) in a small cohort at an academic medical center in the United States. The primary outcome measure will be the percentage of the study group achieving a post operative visual acuity 20/40 Snellen. This percentage will be compared to historical cohorts reported for phacoemulsification cataract surgery (PCS), when performed in academic centers. A secondary outcome will be to determine the actual institutional cost of providing MSICS in the setting of an academic medical center. The hypothesis is that MSICS is appropriate for a teaching environment (as evidenced by a comparable rate of 20/40 acuity or better at 90 days post op, as compared to PCS), and can be provided at a cost that makes visual rehabilitation affordable to the uninsured and underinsured.

NCT ID: NCT02264457 Recruiting - Cataract Clinical Trials

A Intra-patient Comparison of Closed Loop and Plate Haptic Toric Intraocular Lenses

Start date: June 2015
Phase: Phase 4
Study type: Interventional

During cataract surgery an artificial lens is implanted in the eye. These artificial lenses are called intraocular lenses (IOLs) and there are many different types of IOL designs. Your eyes have astigmatism, which is a normal and common characteristic of the eye. If left uncorrected the astigmatism would mean that you would need to wear spectacles for viewing distance objects. New IOL designs called toric IOLs help to correct the astigmatism to improve your vision after cataract surgery. This study has been designed to look at how well a toric IOL corrects this astigmatism so that you do not need to wear spectacles for viewing distance objects. There are many designs of these toric IOLs and for this study we are looking to compare two different designs of toric IOLs by putting one lens in your right eye and a different type of lens in your left eye. Both lenses are commercially available and are commonly implanted IOLs. Using new non-invasive methods we hope to be able to better judge the visual performance of these lenses and the ability of these lenses to correct astigmatism. In addition the study will involve imaging and examining the IOLs to determine the prevalence of any post-operative complications.

NCT ID: NCT02260973 Recruiting - Clinical trials for Cataract, Dry Eye Disease

The Influence of PRN Omega-3 Nutritional Supplement on Visual Acuity

Start date: November 2014
Phase: Phase 2/Phase 3
Study type: Interventional

This is a randomized, masked, placebo controlled study to assess the effect on visual acuity, if any, of the PRN omega-3 nutritional supplement in subjects undergoing cataract surgery.