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Cataract clinical trials

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NCT ID: NCT05143281 Completed - Cataract Clinical Trials

The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1

Start date: December 13, 2021
Phase: Phase 4
Study type: Interventional

To assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) compared to insertion 1-day post-op.

NCT ID: NCT05141370 Completed - Cataract Surgery Clinical Trials

Assessment of a Femtosecond Laser to Perform Capsulorhexis During Cataract Surgery

Start date: February 3, 2022
Phase: N/A
Study type: Interventional

This study is a Pre-market first-in-man clinical investigation to validate performance of a hand-held femtosecond laser named CATSYS.

NCT ID: NCT05133518 Completed - Cataract Clinical Trials

A Study of MELT-300 (Midazolam and Ketamine Sublingual Tablets) for Sedation and Intraoperative Ocular Analgesia in Participants Undergoing Cataract Extraction With Lens Replacement (CELR)

Start date: July 20, 2021
Phase: Phase 2
Study type: Interventional

The primary purpose of the study is to evaluate the efficacy and safety of MELT-300 (Midazolam and Ketamine Sublingual Tablets) and the contribution of midazolam and ketamine components to sedation and during the surgery or ocular analgesia in participants undergoing cataract surgery with lens replacement.

NCT ID: NCT05129566 Completed - Cataract Senile Clinical Trials

Evaluation of Axial Stability of Two Models of Intraocular Lenses in Patients With an Eye Length More Than 26 mm

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

Some parameters, such as a change in the optic tilt and axial decentration, can affect the optical characteristics of intraocular lenses (IOLs) in postoperative period, which leads to residual refractive errors and other complications. The stability of the intraocular lens in the eye is largely dependent on the mechanical design of its haptic support elements. Thus, the new Clareon IOL has a flat haptic with a flexible design that minimizes axial changes and allows the IOL to maintain a stable position in a given plane during compression. Currently there is no published data of the stability for Clareon AutonoMe IOL for long eyes. The purpose of the current study is to evaluate and compare the axis displacement and stability of optical tilt, visual and refractive results in patients after implantation of two different models of intraocular lenses: Clareon AutonoMe (Alcon, USA) and Hoya iSert 251 (Japan) in the long-term postoperative period (after cataract surgery).

NCT ID: NCT05119127 Completed - Cataract Clinical Trials

Rotational Stability of Acrysof IQ Vivity Extended Vision Toric IOL and Refractive Visual Outcome.

Start date: September 30, 2020
Phase: N/A
Study type: Interventional

The purpose of this research is to assess the rotational stability of the AcrySof IQ Vivity Extended Vision Toric IOL and Refractive Visual outcome.

NCT ID: NCT05113979 Completed - Refractive Errors Clinical Trials

Early Feasibility Study to Evaluate the AccuraSee in Correcting Residual Refractive Errors After Cataract Surgery

Start date: March 9, 2020
Phase:
Study type: Interventional

To determine if the intraocular pseudophakic contact lens (IOPCL), referred to as the AccuraSee, corrects residual refractive errors after cataract surgery using a plus powered lens in subjects with ocular pathology previously implanted with a Bausch and Lomb LI61AO or LI61SE monofocal posterior chamber intraocular lens (PCIOL) and to confirm its positional stability and adherence relative to the PCIOL.

NCT ID: NCT05111106 Completed - Cataract Clinical Trials

Symfony Intraocular Lens Retrospective Chart Review

Start date: October 5, 2016
Phase:
Study type: Observational

Retrospective chart review of patients with pre-existing ocular pathology who underwent cataract surgery with implantation of the Symfony IOL.

NCT ID: NCT05090826 Completed - Cataracts Clinical Trials

A Real-World Study for the TECNIS Synergy™ Intraocular Lens

Start date: December 28, 2021
Phase: N/A
Study type: Interventional

This is a prospective and retrospective, single-center, single-arm, open-label clinical study of the TECNIS Synergy™ IOL. The study will enroll up to 100 subjects from a single site in China. All implanted subjects will be followed for 12 months postoperatively.

NCT ID: NCT05085314 Completed - Cataract Clinical Trials

Comfort Operative Ocular Light Study

COOL
Start date: November 18, 2021
Phase: N/A
Study type: Interventional

Digital 3D microscopes require less light and may be more comfortable for patients requiring cataract surgery under topical anesthesia compared to conventional microscopes. To date, no studies have evaluated the comfort and subjective visual sensations related to the light of the 3D digital microscope in cataract surgery patients. The purpose of this study is to evaluate the effectiveness of the Ngenuity 3D digital operating system (Alcon, Fort Worth, TX) compared to conventional microscopes on the comfort and subjective visual sensations related to of patients undergoing initial cataract surgery under topical anesthesia (pure or combined with intravenous sedation).

NCT ID: NCT05069415 Completed - Cataract Clinical Trials

Monofocal IOL Visual Outcomes When Targeting Mini Monovision

Start date: October 4, 2021
Phase: N/A
Study type: Interventional

This study is a 3-month, prospective, up to 2 center, bilateral, randomized subject masked clinical evaluation of a monofocal intraocular lens (IOL) when both eyes are targeted for emmetropia and when the non-dominant eye is targeted for mini monovision (-0.75 D) in patients with or without astigmatism undergoing routine cataract surgery.