Carotid Stenosis Clinical Trial
Official title:
Clinical, Hematological, and Imagiologic Predictors of Postoperative Complications and Long Term Cardiovascular Events After Carotid Endarterectomy With Regional Anesthesia
Establish and validate biomarkers which improve the predictive value of current risk stratification models for patients benefiting from carotid revascularization, outperform existing biomarkers, and reach clinical application standards.
The authors hypothesize FGF-23 and GDF-15 could predict cerebral ischemia, postoperative
complications and long term major cardiovascular events, particularly in patients developing
symptomatic neurologic ischemia after circulation shutdown.
Establish and validate biomarkers which improve the predictive value of current risk
stratification models for patients benefiting from carotid revascularization, outperform
existing biomarkers, and reach clinical application standards.
Clarify the pathophysiology of carotid endarterectomy-related stroke and the role of GDF-15,
FGF-23, BNP and hs-troponin I and other biomarkers in the prognosis of symptomatic carotid
stenosis.
Imagiologic markers are to be included - intima-media; gray weale plaque classification,
cerebral CT Peak wave velocity
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