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NCT ID: NCT04889196 Not yet recruiting - Caries Clinical Trials

The Efficiency and Gingival Health Status of Hall Versus SDF Techniques in the Management of Carious Primary Molars

Start date: September 1, 2021
Phase: Phase 3
Study type: Interventional

PICO question: In Comparison to the hall technique , will silver diamine fluoride have equalvent gingival health status in treatment of carious primary molars? population: children suffering from caries . intervention : silver diamine fluoride. comparison: hall technique outcome: Primary outcome: Gingival health measurement device modified gingival index, measurement unit score(0-1-2) Secondary outcomes: 1. Oral hygiene measurement device modified plaque index , measurement unit score (0-1-2) 2. Time of Treatment measurement device digital chronometer, measurement unit minutes

NCT ID: NCT04794426 Not yet recruiting - Caries Clinical Trials

Post-operative Pain and Child Behavior of Hall Technique Versus SDF in the Management of Carious Primary Molars: RCT

Start date: June 1, 2021
Phase: Phase 3
Study type: Interventional

PICO question: Papulation: children suffering from caries Intervention: Silver Diamine Fluoride Comparison: Hall technique Outcome: Primary Outcome: Intraoperative and postoperative pain Measurement device: Face pain scale Revised8 Measurement unit: Score 0-2-4-6-8-10 Secondary Outcome: 1. Child Anxiety Measurement device: Venham Anxiety rating scale 9 Measurement unit: Six-point scales 0-1-2-3-4-5 2. Child Behavior Measurement device: Venham Behavior rating scale 9 Measurement unit: Six-point scales 0-1-2-3-4-5

NCT ID: NCT04420780 Not yet recruiting - Caries Clinical Trials

Effect of the Use of Xylitol Gum in the Prevention of Caries Lesions in Children Living in Ladakh

CaPreXCh
Start date: August 2021
Phase: N/A
Study type: Interventional

Background: Ladakh is a region administered by India, covering an area slightly larger than Croatia; it is part of the larger region of Kashmir and Jammu. Till now, oral health data on population living in Ladakh are not available. The aim of the present preventive project will be to record the caries prevalence of schoolchildren living in Ladakh and to implement a school-based xylitol program using chewing gums in order to reduce caries incidence. Methods: The protocol of the Caries Prevention Xylitol in Children (CaPreXCh) trial is designed as a triple-blind randomized, controlled, parallel-group clinical trial in children aged 5-14 years. The study will be carried out from August 2021 to August 2024 in Zanskar Valley (Ladakh). Participants will be randomly allocated into two groups: subjects who will receive a 100% xylitol chewing gum, and those who will receive a 22% xylitol gum. The subjects will be instructed to chew a total of 6 pellets for 5 min divided into 3 intakes a day (2 in the morning, 2 after the midday meal and 2 in the afternoon) for one school-year. Clinical examination will comprise an oral examination: caries index (ICDAS scores), bleeding on probing recording and evaluation of plaque pH fluctuation after sucrose challenge and will be performed at baseline (t0) and repeated 12 months at the end of the chewing-gum administration period (t1) as interim examination, after 12 months (t2) and 24 months (t3) after the end of the experimental period (chewing gum use). The primary outcome will be the caries increment measured both at enamel and dentinal level. Data analysis will be conducted through Kaplan-Meyer graphs to evaluate caries increment as primary outcome, and the methods will be compared to each other with Cox regression with shared frailty. The net caries increment for initial, moderate and severe caries level, using ICDAS (Δ-initial, Δ-moderate and Δ-severe), will be calculated. Discussion: This is the first clinical trial to assess the effect of chewing gum containing only xylitol as sweeteners for caries prevention. Moreover, the children object of this study is a population with special living conditions.

NCT ID: NCT03656432 Not yet recruiting - Caries Clinical Trials

Effect of CPP-ACP With/Without Fl on White Spot Lesion,Salivary pH and fl Release in High Caries Risk Patients

Start date: October 2018
Phase: Phase 3
Study type: Interventional

Effect of CPP-ACP pastes with/without Fluoride on White spot lesion progression, salivary pH and fluoride release in high caries risk Patients, over 3 month period using VistaCam, Digital pH meter and Selective ion electrode.

NCT ID: NCT03224962 Not yet recruiting - Caries Clinical Trials

Reliability of Fluorescent Camera in Diagnosis of Occlusal Carious Lesion

Start date: August 2017
Phase: N/A
Study type: Observational

This study will be conducted to compare the diagnostic predictive values of a light induced fluorescence camera and Caries detection dye versus visual assessment method in identification of occlusal carious lesion.

NCT ID: NCT02933463 Not yet recruiting - Caries Clinical Trials

Clinical Effectiveness of Embrace Wetbond and Clinpro as Pits and Fissure Sealants in Young Permanent Molars

Start date: October 2016
Phase: N/A
Study type: Interventional

This study is designed to clinically evaluate the retention and development of caries when using self-priming (Embrace wetbond) and conventional flowable composite (Clinpro) as pit and fissure sealant in young first permanent molars.

NCT ID: NCT00531154 Not yet recruiting - Obesity Clinical Trials

Evaluation of the Dental Health Condition in Obesity Patients Before and After Bariatric Surgery

Start date: n/a
Phase: N/A
Study type: Observational

The aim of this study is to investigate whether there was an association between obesity and periodontitis, tendency to caries and periapical lesions. People who have a higher body mass index produce cytokines (hormone-like proteins), that lead to systemic/chronic inflammation (like periodontitis and periapical lesions), and obesity related dietary habits could result in an increment of dental caries because both the amount and the frequency of sucrose ingestion are important factors associated with the aetiology of the oral disease.

NCT ID: NCT00421577 Not yet recruiting - Caries Clinical Trials

Technique for Localization of Caries Associated Bacteria on Tooth Surfaces.

Start date: n/a
Phase: N/A
Study type: Observational

There is a simple laboratory technique for localization of caries associated bacteria on tooth surfaces by taking an impression of the teeth with a material containing sucrose. The purpose of this study is to check whether the technique can be incorporated into dental clinics as diagnostic tool comparing to other diagnostic methods available.