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Caries, Dental clinical trials

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NCT ID: NCT04342858 Active, not recruiting - Caries,Dental Clinical Trials

Prospective Randomized Controlled Trial for Prevention of Demineralization During Fixed Orthodontic Treatment

Start date: September 15, 2017
Phase: Phase 2
Study type: Interventional

Treatment with fixed orthodontic appliances is often associated with pain, which poses great challenges in the efficient brushing of the teeth thus making the teeth more vulnerable to plaque formation. Treatment duration with fixed orthodontic appliances usually extends to 18 months or even longer in some cases. This prolonged vulnerability to plaque formation frequently leads to demineralization of teeth. There is also an increase in the number of plaque retentive sites due to the fixed appliances, leading to a rapid change in the bacterial composition of the dental plaque, particularly in the number of acidogenic bacteria. The resulting enamel decalcification is also known as white spot lesions (WSLs), which is an early sign of demineralization of enamel. Enamel WSLs (EWSLs) can be observed even as early as four weeks from the start of fixed orthodontic treatment. The occurrence of EWSLs adjacent to the orthodontic brackets ranges from 15 to 85%. The incidence of EWSLs development is higher in orthodontic patients as compared to the development of similar lesions in non-orthodontic patients. These EWSLs are not aesthetically pleasing and is certainly unacceptable when it develops during fixed orthodontic treatment that is usually performed in patients who often seek such treatment to improve their aesthetics. Additionally, even if the outcome of fixed orthodontic treatment is superior from well-aligned teeth, aesthetics can be greatly compromised with EWSLs. Therefore, the prevention of such lesions is an important concern for orthodontists. Though professionally applied topical fluoride varnish helps in remineralization of EWSLs, an adequate supply of calcium and phosphate ions is essential for remineralization. Therefore, EWSLs on maxillary teeth could be prevented and remineralized by the use of advanced novel topical fluoride varnish with added calcium and phosphate-based delivery system.

NCT ID: NCT04303767 Not yet recruiting - Caries,Dental Clinical Trials

The Effect of Casein Phosphopeptide Amorphous Calcium Phosphate on Affected Dentine

Start date: March 1, 2020
Phase: Phase 2
Study type: Interventional

Teeth selected for intervention with Atraumatic Restorative Treatment will receive Glass Ionomer restorations (control) or MI varnish (test) before receiving the Glass Ionomer restoration

NCT ID: NCT04286256 Completed - Caries Clinical Trials

Using Motivational Interviewing To Reduce Parental Risk-Related Behaviors For Early Childhood Caries

Start date: October 1, 2011
Phase: N/A
Study type: Interventional

The study's aim was to investigate if a motivational interviewing intervention (MI) improved oral self-care behaviors of AIAN caregivers of infants and determine if the MI intervention promoted positive changes in caregivers' ECC risk-related behaviors.

NCT ID: NCT04279574 Active, not recruiting - Caries,Dental Clinical Trials

Clinical Performance of Chairside CAD/CAM Restorations

Start date: August 26, 2020
Phase: N/A
Study type: Interventional

This investigation will be a longitudinal clinical trial to study the long-term clinical performance of a resin cement for chairside CAD/CAM restorations. Lithium disilicate chairside CAD/CAM onlays will be adhesively bonded using a selective enamel etch technique with an adhesive. Full contour zirconia crowns will be cemented using a self-adhesive resin cement.

NCT ID: NCT04274855 Recruiting - Anxiety Disorders Clinical Trials

Effect of Trait Anxiety in Women on Oral Health Status and Oral Health Care-Seeking Behavior

Start date: February 5, 2020
Phase:
Study type: Observational

Trait anxiety is the tendency of an individual to perceive environmental stimuli such as different events and situations as threatening; it's stable and reflects how an individual generally feels. In 2015, it was estimated that 3.6% of the population lived with anxiety disorders globally, i.e. approximately 264 million people lived with anxiety disorders worldwide of which 31.36 million resided in the Eastern Mediterranean region, that's to say, 10% of the global number of anxiety cases. Moreover, females were more affected than males in a proportion of 4.6% as opposed to 2.6% respectively. The prevalence of anxiety has increased by 14.9% from 2005 to 2015. In addition, in 2017, approximately 42 million new cases were recorded globally. In Egypt, the total number of anxiety cases were more than 3 million in 2015 thus indicating that 4.2% of the total population lived with anxiety. Anxiety may affect the individual's utilization of dental services and predispose to a delay in seeking dental treatment and thus might compromise the overall oral health. Accordingly, this study aims to investigate the effect of trait anxiety on the oral health status of women and determine their behavior towards the utilization of dental services. To our knowledge, no previous research has been conducted to assess such relationship in Egypt.

NCT ID: NCT04251858 Enrolling by invitation - Clinical trials for Periodontal Diseases

Evaluation of Oral Condition and the Effect of Dental Treatment on Physical Parameters of Athletes

Start date: March 30, 2019
Phase: N/A
Study type: Interventional

It is essential that athletes have perfect general health. Oral health plays an important role in this healthy framework necessary so that the results that must be achieved by athletes are not influenced. Inflammatory and / or infectious processes such as periodontal disease, caries, or even joint problems such as temporomandibular joint dysfunction can affect performance or impair participation in training and competitions.

NCT ID: NCT04147091 Completed - Caries,Dental Clinical Trials

Nano-hydroxyapatite and Ozone - Effect on Approximal Initial Caries

Start date: February 2012
Phase: Phase 2/Phase 3
Study type: Interventional

Objectives: to assess the efficiency of three methods of enamel remineralization on initial approximal caries: 1. a nano-hydroxyapatite gel, 2. gaseous ozone therapy 3. combination of a nano-hydroxyapatite gel and ozone. Materials and Methods: Patients (n=92, age 20-30y) with initial approximal enamel lesions on premolar and molar teeth (n=546) randomly allocated to three groups subjected to a 6-months treatment: Group I: domestic nano-hydroxyapatite remineralizing gel, group II: in-office ozone therapy, group III: both remineralizing gel and ozone therapy. Caries lesions assessed on bitewing radiographs at baseline, after 1 year and after 2 years.

NCT ID: NCT04122508 Completed - Anxiety Clinical Trials

Are Dental Neglect and the Siblings Risk Factors in Children

Start date: January 1, 2019
Phase:
Study type: Observational

Neglect insidiously affects a child's overall health in all aspects. The aim of this study was to determine whether the presence of siblings caused dental neglect, and whether there was a relationship between dental neglect and anxiety.

NCT ID: NCT04105985 Withdrawn - Clinical trials for Apical Periodontitis

Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Endodontics

Start date: August 2020
Phase: Phase 2
Study type: Interventional

The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia.

NCT ID: NCT04104789 Withdrawn - Clinical trials for Apical Periodontitis

Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - General

Start date: September 2020
Phase: Phase 2
Study type: Interventional

The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia.