Cardiovascular Diseases Clinical Trial
Official title:
The Impact of 3 Days of Reduced Physical Activity on Endothelial Function and Glycemic Control in Active Older Adults
Verified date | August 2022 |
Source | Old Dominion University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Physical inactivity is known to increase post meal blood sugar levels in young, active populations. However, how quickly this may occur in active, older adults is not clear. Further, the relationship between blood vessel health and blood sugar disturbances which occur to acute physical inactivity is not clear. It is unknown if impairments in blood vessel function precede increases in blood sugar levels that occurs with inactivity in an aging population. This study aims to determine if short term reductions in physical activity impair blood vessel health and blood glucose control to a greater extent in an aging population compared to a young population. The investigators hypothesize that 3 days of reduced physical activity will result in impaired blood vessel function and glycemic control in an aged population.
Status | Completed |
Enrollment | 20 |
Est. completion date | January 30, 2022 |
Est. primary completion date | January 30, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: 1. 55 years and older, 18-40 years old 2. Healthy, physically active, performing at least 90 min/week of physical activity 3. Free of physical limitations that may interfere with alterations in daily physical activity levels Exclusion Criteria: 1. Physician diagnosed metabolic disease, HIV, hepatitis, or tuberculosis. 2. Body weight change of greater than 5% within the previous 2 months 3. Smoking within the previous 2 months. 4. Taking medications that alter blood glucose levels |
Country | Name | City | State |
---|---|---|---|
United States | Old Dominion University | Norfolk | Virginia |
Lead Sponsor | Collaborator |
---|---|
Leryn Reynolds |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in glycemic control during a reduced physical activity state | The change in blood glucose levels measured following consumption of a meal will be assessed before inactivity and following 3 days of inactivity. | The change of blood glucose values from pre-inactivity and following 3 days of inactivity |
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