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The Role of Stem Cells on Immune Cells in the Development of Cardiovascular Diseases — ATHEROSTEM  

Cardiovascular Diseases Clinical Trial

Official title:
Phenotypic and Epigenetic "Trained Immunity" Characteristics of Hematopoietic Stem and Progenitor Cells in Patients With Established Atherosclerosis

Clinical Trial Summary

An observational pilot proof-of-principle study. 15 patients with significant coronary artery disease and 15 matched controls. To investigate whether long-term activation of the innate immune system, named 'trained innate immunity', occurs at the level of the bone marrow progenitor cells in patients with significant coronary artery disease and whether this correlates with the proinflammatory phenotype of monocytes.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03172507
Study type Observational [Patient Registry]
Source Radboud University
Contact
Status Completed
Phase
Start date September 20, 2017
Completion date October 1, 2018
View Details
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