Heart Failure Clinical Trial
Official title:
Comparing Clinical Profile and Outcomes of Acute Coronary Syndrome in Diabetic and Non-Diabetic Patients
This study aims to compare the clinical profile and outcomes of acute coronary syndrome patients with diabetes and without diabetes.
Adult patients (≥ 18 years of age) with acute coronary syndrome which are diagnosed under
International Classification of Disease (ICD-10) coding of I24.9 were included in this study.
The inclusion criteria are patients with primary diagnosis of I24.9 and with a complete
record of prior medical and treatment history, electrocardiographic findings, cardiac marker
results and outcomes. Participants were grouped into 2 groups - diabetic and non-diabetic
based on history of diabetes prior to ACS. Diagnosis of ACS was made based on clinical,
electrocardiographic and cardiac marker findings found in the medical record.
Data such as age, sex, ethnic, education, prior medical and treatment history,
electrocardiographic and cardiac enzyme results as well as outcomes were collected from the
patients' medical records. Outcomes of interest were defined as either concomitant heart
failure, acute lung edema, malignant arrhythmia, mortality or combinations of them as
diagnosed in the medical records. Heart failure is defined based on echocardiographic
findings from the medical records. Acute Lung Edema is defined based on medical records or
reported clinical findings of lung edema - rhonchi reported in 1/3 of the lungs with oxygen
saturation <90%. Whereas malignant arrhythmia is defined as the presence of ventricular
tachycardia (VT) or ventricular fibrillation (VF).
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