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Capsule Opacification clinical trials

View clinical trials related to Capsule Opacification.

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NCT ID: NCT03317847 Completed - Inflammation Eye Clinical Trials

Bromfenac Versus Dexamethasone After Cataract Surgery

BVD
Start date: October 16, 2017
Phase: Phase 4
Study type: Interventional

The aim of the study is to compare bromfenac to dexamethasone eye drops to control inflammation after cataract surgery. Inflammation in the anterior chamber of the eye will be measured by a Laser Flare Photometer (LFP).

NCT ID: NCT03276182 Completed - Cataract Patients Clinical Trials

Evaluation of Meibomian Gland Dysfunction Before and After Cataract Surgery

Start date: October 5, 2015
Phase: N/A
Study type: Interventional

This study will compare cataract patients before and after phacoemulsification. Evaluations will be performed before and 1 and 3 months following cataract surgery, including parameters of dry eye syndrome and MGD. Dry eye syndrome parameters included TBUT, Schirmer's test type I, Oxford staining score, and the Ocular Surface Disease Index (OSDI) Questionnaire. MGD parameters consisted of lipid layer thickness (LLT), lid margin abnormality, meibum quality, meibum expressibility, MG orifice obstruction, MGD stage, and MG dropout.

NCT ID: NCT03192826 Completed - Ocular Hypertension Clinical Trials

Brinzolamide/Brimonidine Combination vs Brimonidine 0.2% in the Prevention of IOP Rise After Nd-YAG Laser Capsulotomy

Start date: June 20, 2016
Phase: Phase 4
Study type: Interventional

To compare the efficacy of a Brinzolamide/Brimonidine fixed combination (FC) with Brimonidine 0.2% in preventing intraocular pressure (IOP) elevations after neodymium: yttrium-aluminum-garnet (Nd:YAG) laser posterior capsulotomy.

NCT ID: NCT03184428 Completed - Clinical trials for Posterior Capsule Opacification

Posterior Capsule Opacification Following Cataract Surgery With Implantation of the MICS IOL L313

Start date: October 1, 2015
Phase:
Study type: Observational

This study collects intra- and postoperative data from the patients´charts retrospectively and evaluates retro- and prospectively the rate of posterior capsule opacification (PCO) following implantation of the intraocular lens L 313.

NCT ID: NCT03097562 Completed - Cataract Clinical Trials

Wound Architecture and Functional Outcome After Cataract Surgery With Manual vs.Femtosecond Laser Assisted Procedures

CATALYS
Start date: February 2, 2017
Phase: N/A
Study type: Interventional

This study is the long term analysis of two types of FSL 3-plane corneal wound profiles, namely CT1 and CT2 obtained after a FSL cataract surgery.

NCT ID: NCT03035864 Completed - Ocular Discomfort Clinical Trials

A 8 Weeks Study to Evaluate Efficacy & Safety of rhNGF vs Vehicle in Patients After Cataract and Refractive Surgery

Start date: January 12, 2017
Phase: Phase 2
Study type: Interventional

The primary objective of this exploratory study is to assess preliminary efficacy and safety of rhNGF when administered as eye drops to patients after cataract and refractive surgery. The main criteria for evaluation were: - Change from baseline in SANDE scores for severity and frequency assessed at 8 weeks of treatment (primary efficacy endpoint) - Changes in Cornea vital staining with fluorescein (National Eye Institute [NEI] scales) assessed at 8 weeks of treatment (co-primary efficacy endpoint) - Changes in conjunctiva vital staining with fluorescein (NEI scales) (secondary efficacy endpoint); - Changes in Tear Film Break-Up Time (TFBUT)(secondary efficacy endpoint); - Changes in Cochet-Bonnet corneal aesthesiometry (secondary efficacy endpoint); - Changes in Nerve count and morphology at scanning laser in vivo corneal confocal microscopy (only patients who had Laser-Assisted In situ Keratomileusis [LASIK] surgery) (secondary efficacy endpoint); - Changes in SANDE scores (face values) for severity and frequency (secondary efficacy endpoint); - Incidence and frequency of treatment-emergent adverse events (TEAEs), assessed throughout the study (safety endpoint).

NCT ID: NCT02975895 Completed - Inflammation Clinical Trials

Outcome of Different IOLs in Patients With and Without Uveitis

Start date: December 30, 2016
Phase: N/A
Study type: Interventional

Cataract, is a clouding of the lens in the eye gradually leading to reduction of the visual acuity. In most cases it can be managed with surgery, removing the own lens and replacing it with an artificial lens, intraocular lens (IOL). These lenses are made in different materials with different properties. Uveitis refers to an inflammation in the iris, ciliary body and choroid. Patients with this disease have an increased risk of developing cataract due to the inflammation itself and treatment with steroids. They also have an increased risk of complications during surgery and postoperatively. In this group the selection of IOL might be of greater importance. The aim of this prospective randomized controlled study is to compare the outcome of hydrophobic and hydrophilic intraocular lenses in patients with and without uveitis

NCT ID: NCT02968290 Completed - Clinical trials for Posterior Capsule Opacification

Quantification of Posterior Capsule Opacification in Pediatric Cataract

Cataract
Start date: May 1, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to quantify the opacity of posterior capsule in pediatric cataract comparing two intraocular lens materials.

NCT ID: NCT02888210 Completed - Cataract Clinical Trials

A Study Assessing Safety and Efficacy of MD-15 Intraocular Lens in Patients With Aphakic Eye After Cataract Surgery

Start date: September 3, 2016
Phase: Phase 3
Study type: Interventional

To evaluate safety and efficacy of MD-15 intraocular lens implanted into the aphakic eyes

NCT ID: NCT02842151 Completed - Cataract Clinical Trials

Optimizing the Assessment of Refractive Outcomes After Cataract Surgery

Start date: September 21, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate current available assessments (automated vs. manual) with which manifest refraction data and biometric variables are obtained to understand if data from an automated refractor can be utilized to optimize the A-constant as well as manual subjective refraction (ie, to a clinically insignificant difference). The A-constant is the calculated number that helps the surgeon determine which IOL should be implanted in the eye during cataract surgery.