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Transarterial Chemoembolization (TACE) Plus Bevacizumab for Liver Metastases

Cancer Clinical Trial

Official title:
An Open-Label Pilot Study to Evaluate Efficacy and Safety of Bevacizumab Via Transarterial Chemoembolization (TACE) in Patients With Liver Metastases

Clinical Trial Summary

Trans arterial chemoembolization (TACE) has emerged as a treatment option for chemotherapy-refractory diseases in Liver metastases. By delivering chemotherapy agents directly to the tumor site, TACE can maximize local drug concentrations and reduce systemic adverse reactions. Bevacizumab is a monoclonal antibody that functions as an angiogenesis inhibitor. It works by slowing the growth of new blood vessels by inhibiting vascular endothelial growth factor A (VEGF-A). The application of Bevacizumab during TACE has not been reported. In this study, we will evaluate the the overall survival (OS)态efficacy, and safety of the application of Bevacizumab during TACE in patients with Liver Metastases by designing an open, single-arm phase II clinical study.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06311851
Study type Interventional
Source Pardis Noor Medical Imaging and Cancer Center
Contact Shahram Akhlaghpoor, M.D
Phone +9802192008808
Email shahram_ak@yahoo.com
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date April 1, 2024
Completion date December 1, 2024
View Details
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