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Clinical Trial Summary

A first-in-human study using BIO-106 as a single agent and in combination with pembrolizumab in advanced cancers.


Clinical Trial Description

This is an open-label, Phase 1/2, first-in-human (FIH), multiple ascending dose and dose-expansion study of BIO-106 administered as monotherapy and in combination with pembrolizumab. Phase 1 will define the maximum tolerated dose (MTD) or recommended Phase 2 dose (RP2D) of BIO-106 that can be advanced to Phase 2. Phase 2 will define the preliminary efficacy of these regimens in the setting of advanced solid tumors with high unmet medical needs. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05320588
Study type Interventional
Source BiOneCure Therapeutics Inc.
Contact BiOneCure Therapeutics Inc.
Phone (240) 912-9101
Email Starbridge-1@bionecure.com
Status Recruiting
Phase Phase 1/Phase 2
Start date March 25, 2022
Completion date April 2027

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