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Clinical Trial Summary

This study is being done because the investigators would like to learn more about how well the COVID-19 vaccine works in participants with cancer or those who have received a transplant or cellular therapy. Primary Objective Assess the immunogenicity to COVID-19 vaccination in patients with cancer and/or transplant and cellular therapy (TCT) recipients. Secondary Objectives - Evaluate the antibodies response to COVID-19 vaccination in immunocompromised patients. - Evaluate the T cell response to COVID-19 vaccination in immunocompromised patients. Exploratory Objectives - Assess incidence and severity of COVID-19 infections by 6 months following immunization with a SARS CoV-2 vaccine. - Assess the durability immune response to COVID-19 vaccination. - Assess the immunogenicity of COVID-19 vaccination in immunocompetent children and adolescents without cancer and have not undergone transplant or received cellular therapy.


Clinical Trial Description

The investigator will collect a blood sample (about 1 teaspoon each time) from the participant when the participant receive the COVID-19 vaccine(s) as well as an additional blood samples 6 months after the last COVID-19 vaccine. The participant will be on the study for about 6 months after the last vaccine. After the six-month blood sample is collected, the participant will be off study. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05164016
Study type Observational
Source St. Jude Children's Research Hospital
Contact Diego Hijano, MD
Phone 866-278-5833
Email [email protected]
Status Not yet recruiting
Phase
Start date February 2022
Completion date December 31, 2024

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