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Clinical Trial Summary

Evaluation of antibody response against SARS-CoV-2 vaccination in patients treated with IO-treatment, in comparison with antibody titers in patients treated with non-IO treatment.


Clinical Trial Description

Blood samples will be analyzed to determine the magnitude of SARS-CoV-2 immunity in cancer patients treated with immunotherapy by quantifying antibodies and other tumor or blood-based biomarkers against SARS-CoV-2 epitopes following vaccination. We will also explore for potential development of autoantibodies and other blood-based biomarkers, following SARS-CoV-2 vaccination, and their correlation with clinical manifestation of IO related immune-related adverse events. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05062525
Study type Observational
Source University Health Network, Toronto
Contact
Status Completed
Phase
Start date September 28, 2021
Completion date September 28, 2021

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