Clinical Trials Logo
  1. Home
  2. Cancer
  3. NCT04988490
  4. Details
NCT04988490 Clinical Trial

Quantification of Cannabinoids and Comparison to Post-Surgical Pain Medication Requirements and Surgical Outcomes

Cancer Clinical Trial

Official title:
Quantification of Endo- and Phytocannabinoids With Comparison to Pain Medication Requirements and Surgical Outcomes for Patients Undergoing Abdominal Surgery for Cancer

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04988490
Other study ID # 21-3544.cc
Secondary ID P30CA046934
Status Recruiting
Phase
First received
Last updated
Start date September 22, 2021
Est. completion date February 2026

Study information
Verified date June 2024
Source University of Colorado, Denver
Contact Camille Stewart
Phone 2566941233
Email camille.stewart@cuanschutz.edu
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To determine how daily cannabis use affects surgical outcomes.

Description:

To determine if patients who are daily cannabis users that are undergoing inpatient abdominal surgery for the treatment of cancer are different from non-cannabis users regarding phytocannabinoid and endocannabinoid levels, pain scores, pain medication requirements, and surgical complications.

Recruitment information / eligibility
Status Recruiting
Enrollment 80
Est. completion date February 2026
Est. primary completion date May 18, 2025
Accepts healthy volunteers No
Gender All
Age group 21 Years and older
Eligibility Inclusion Criteria: - Patients > 21 years old - Undergoing abdominal surgery for the treatment of cancer - Report no cannabis use in the last year or daily cannabis use Exclusion Criteria: - patients with chronic pain, chronic pain syndrome on opioids - female patients who are pregnant or lactating - patients who report use of illicit substances

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States Colorado Research Center Denver Colorado

Sponsors (2)
Lead Sponsor Collaborator
University of Colorado, Denver National Cancer Institute (NCI)

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Postoperative opioid consumption Postoperative opioid consumption among daily cannabis using and non-cannabis using patients undergoing abdominal surgery for cancer 30 days
Primary Correlation of postoperative opioid consumption Correlation between serum phytocannabinoid and endocannabinoid levels, pain scores, and postoperative opioid consumption 30 days
Primary Correlation of postoperative complications Correlation between 30-day post-operative complications, preoperative, and postoperative phytocannabinoid and endocannabinoid levels 30 days
See also
  Status Clinical Trial Phase
Recruiting NCT05346796 - Survivorship Plan HEalth REcord (SPHERE) Implementation Trial N/A
Recruiting NCT05094804 - A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents Phase 1/Phase 2
Completed NCT04867850 - Effect of Behavioral Nudges on Serious Illness Conversation Documentation N/A
Enrolling by invitation NCT04086251 - Remote Electronic Patient Monitoring in Oncology Patients N/A
Completed NCT01285037 - A Study of LY2801653 in Advanced Cancer Phase 1
Completed NCT00680992 - Study of Denosumab in Subjects With Giant Cell Tumor of Bone Phase 2
Completed NCT00062842 - Study of Irinotecan on a Weekly Schedule in Children Phase 1
Active, not recruiting NCT04548063 - Consent Forms in Cancer Research: Examining the Effect of Length on Readability N/A
Completed NCT04337203 - Shared Healthcare Actions and Reflections Electronic Systems in Survivorship N/A
Recruiting NCT04349293 - Ex-vivo Evaluation of the Reactivity of the Immune Infiltrate of Cancers to Treatments With Monoclonal Antibodies Targeting the Immunomodulatory Pathways N/A
Terminated NCT02866851 - Feasibility Study of Monitoring by Web-application on Cytopenia Related to Chemotherapy N/A
Active, not recruiting NCT05304988 - Development and Validation of the EFT for Adolescents With Cancer
Completed NCT04448041 - CRANE Feasibility Study: Nutritional Intervention for Patients Undergoing Cancer Surgery in Low- and Middle-Income Countries
Completed NCT00340522 - Childhood Cancer and Plexiform Neurofibroma Tissue Microarray for Molecular Target Screening and Clinical Drug Development
Recruiting NCT04843891 - Evaluation of PET Probe [64]Cu-Macrin in Cardiovascular Disease, Cancer and Sarcoidosis. Phase 1
Active, not recruiting NCT03844048 - An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial Phase 3
Completed NCT03167372 - Pilot Comparison of N-of-1 Trials of Light Therapy N/A
Completed NCT03109041 - Initial Feasibility Study to Treat Resectable Pancreatic Cancer With a Planar LDR Source Phase 1
Terminated NCT01441115 - ECI301 and Radiation for Advanced or Metastatic Cancer Phase 1
Recruiting NCT06206785 - Resting Energy Expenditure in Palliative Cancer Patients