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A Study of MEDI1191 in Sequential and Concurrent Combination With Durvalumab in Subjects With Advanced Solid Tumors

Cancer Clinical Trial

Official title:
A Phase 1, Open-label, Dose-escalation and Expansion Study of MEDI1191 Administered Intratumorally as Monotherapy and in Combination With Durvalumab in Subjects With Advanced Solid Tumors

Clinical Trial Summary

To evaluate MEDI1191 administered intratumorally in sequential and concurrent combination with intravenous durvalumab in patients with solid tumors.

Clinical Trial Description

This is a multicenter, open-label study to evaluate MEDI1191 delivered by intratumoral injection in sequential and concurrent combination with intravenous durvalumab to subjects with solid tumors. The study has a dose escalation design using mTPI-2 to evaluate a range of doses. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03946800
Study type Interventional
Source MedImmune LLC
Contact
Status Completed
Phase Phase 1
Start date May 8, 2019
Completion date August 24, 2023
View Details
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