Cancer Clinical Trial
Official title:
Resistance Training to Improve Fatigue and Physical Function in Postmenopausal Breast Cancer Survivors
This study will begin to fill a knowledge gap by determine whether changes in kynurenine metabolism occur following Resistance Training (RT) and relate to reductions in inflammation and improved behavioral and physical function as this may identify potential targets for interventions to promote cancer recovery.
Interventions that reduce pro-inflammatory cytokines with resultant stimulation of kynurenine
metabolism may be increasingly important in Breast Cancer Survivors (BCS) to prevent
susceptibility to cancer associated fatigue, depression, and declines in muscle mass and
function.
There is emerging evidence that supports exercise as a non-pharmacological therapy to prevent
cancer recurrence, sedentary behaviors, and obesity during cancer survivorship . It seems
that interventions that include resistance training (RT) are most efficacious at reducing
fatigue in BCS This study will begin to fill a knowledge gap by determine whether changes in
kynurenine metabolism occur following RT and relate to reductions in inflammation and
improved behavioral and physical function as this may identify potential targets for
interventions to promote cancer recovery.
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