Cancer Clinical Trial
Official title:
Fragmentation of Elastin as a Biological Marker of Frailty and Impact in Tumor Progression in Elderly Patients With Cancer
The aim of the study is to evaluate frailty in patients aged ≥ 65 years with cancer. The
elderly population is very heterogeneous, it is necessary to evaluate these elderly patients
before treatment to assess the risk-benefit balance. To date, this assessment relies on
subjective clinical methods often not optimal, and slow to implement. An innovative method of
evaluation could be the determination of elastin peptides. Indeed, the rate of these
peptides, which are linked to serious conditions associated with age, rising inexorably with
age and dose could help determine more objectively the type of treatment to offer older
patients.
Expected results : This study will allow better identification of the group of frail elderly
through more relevant biological marker that clinical assessment, often subjective and not
available within a period compatible with the treatment of newly diagnosed cancer. This
biological assessment will also enable optimal management of elderly patients in particular
by allowing the geriatrician better efficiency.
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