Cancer Clinical Trial
Official title:
An Open Label, Dose Escalation Safety and Tolerability Trial of the Combination of s.c. Recombinant Human IL-21 (rIL-21) and Sunitinib (Phase 1) Followed by an Open Label Stratified Randomized 2-arm Trial of rIL-21 Plus Sunitinib Versus Sunitinib Alone (Phase 2a) in Subjects With Stage IV Renal Cell Carcinoma
This phase 1/2a trial is conducted in Europe. The first part of the trial is a dose
escalation safety trial determining the maximum tolerated dose of rIL-21 when administered
in combination with sunitinib.
The second part, scheduled to start in September 2008, is a randomised 2-arm trial comparing
the anti-tumour effect of rIL-21 plus sunitinib with sunitinib alone.
n/a
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