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Cancer Survivor clinical trials

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NCT ID: NCT04189770 Recruiting - Cancer Survivor Clinical Trials

Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate Cancer Survivors and Their Partners

Start date: February 26, 2020
Phase:
Study type: Observational

This trial studies the day-to-day stress, social support, and health lifestyle behaviors (such as physical activity and nutrition) in African American patients with stage 0-III prostate cancer survivors and their partners. How patients cope with stress may affect their lifestyle behaviors. This study may help understand not only survivors' behaviors but also partners' behaviors and how they interact.

NCT ID: NCT04009044 Recruiting - Cancer Survivor Clinical Trials

Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast

Start date: February 17, 2020
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well topical afimoxifene works in treating patients with breast cancer who have undergone radiation therapy on one breast. Topical afimoxifene is a quick-drying medicated gel that may block the growth of breast cancer cells when applied to the breast skin. The purpose of this research is to determine what effect, if any, differences in skin type between women have on the delivery of topical afimoxifene to the breast tissue, and whether radiation affects the delivery of topical afimoxifene to breast tissue.

NCT ID: NCT03932786 Recruiting - Cancer Survivor Clinical Trials

Studying Health Outcomes After Treatment in Patients With Retinoblastoma

RIVERBOAT
Start date: January 24, 2019
Phase:
Study type: Observational

This trial studies health outcomes after treatment in patients with retinoblastoma. Gathering health information over time from patients and family members through vision assessments, samples of tissue and saliva, and questionnaires may help doctors learn more about what causes retinoblastoma, identify long-term health outcomes for patients with retinoblastoma, and find out which therapies may be the best for treating retinoblastoma

NCT ID: NCT03913962 Recruiting - Diabetes Clinical Trials

Health and Exercise Response in Children With Chronic and Auto-immune Pathologies

HERCCULE
Start date: May 2, 2019
Phase: N/A
Study type: Interventional

The aim of the present project is to assess the effects of the chronic diseases and their associated treatments chronic paediatric diseases (CPD), to further understand their impact on physical fitness for public health perspectives. This is an innovative approach in the treatment of chronic paediatric diseases . This project should yield results that help improving treatments for children and adolescents with chronic paediatric diseases throughout physical activity as therapy, reduced pain, fatigue and inflammation, and improvement in physical fitness and life quality. The originality and novelty of this project is to combine architectural, functional and metabolic components of skeletal muscle to further understand the impact of chronic paediatric diseases as a function of treatment, disease activity and maturation status (prepubertal, pubertal or post pubertal). This study will aim at assessing muscular function (force production capacity and fatigability) in specific or ecologic situations so as to get information about muscle functioning on isolated muscle group (here knee extensors) or during whole body exercise. Moreover, results arising from muscle architecture or quality will allow understanding the decrease in strength or endurance reported in the literature. The data collected will allow us to further understand the impact of the disease on structural, functional and metabolic parameters. Finally, the understanding of these alterations will provide information enabling to establish recommendations in physical activity (PA) to reduce or even counter the effect of the chronic inflammation and prevent at long-term overweight and cardiovascular risks. The long-term objective is to contribute establishing recommendations or guidelines for prescribing physical activity during medical therapy. Values obtained in pathological children will be compared to those of control children matched for gender and maturation.

NCT ID: NCT03880422 Recruiting - Obesity Clinical Trials

Nutrition and Exercise Interventions in Reducing Androgen Deprivation Therapy-Induced Obese Frailty in Prostate Cancer Survivors

Start date: May 2, 2019
Phase: N/A
Study type: Interventional

This trial studies how well nutrition and exercise interventions work in reducing androgen deprivation therapy-induced obese frailty in prostate cancer survivors. Individualized nutrition and exercise advice for prostate cancer patients on androgen deprivation therapy may help to reduce obese frailty and change the levels of myokines in blood.

NCT ID: NCT01231932 Recruiting - Breast Cancer Clinical Trials

Characterizing Fatigue Experienced by Cancer Patients Receiving Primary Treatment and Cancer Survivors

Start date: February 4, 2011
Phase:
Study type: Observational

Background: - Fatigue is a common side effect of cancer and its treatment. Up to 96% of patients with cancer have fatigue. The cause of fatigue in people with cancer or those receiving treatment is poorly understood, making fatigue hard to treat. More research is necessary to understand why cancer patients experience fatigue. Previous research has shown that fatigue may be caused by a number of factors, including problems with the immune system response of the body while undergoing cancer treatment. The researchers of this study are trying to understand how the immune system and other chemicals of the body change while a person receives cancer treatment and how these changes play a role in causing fatigue. The researchers are also interested in how a person s quality of life is affected by fatigue. Objectives: - To study fatigue in individuals who have cancer, are receiving cancer treatment, or have completed cancer treatment. Eligibility: - Individuals at least 18 years of age. - Receiving cancer treatment, OR completed primary treatment for cancer (e.g., cancer survivors), OR on active surveillance for localized cancer. Design: - This study involves an initial screening visit and up to three outpatient visits. - Participants will be screened with a medical history review (can be done virtually) and blood tests. A physical exam might also occur. - Participants undergoing cancer treatment that has a clear completion date, will have the following visits: - Before the start of treatment. - At the end of treatment. - At least 3 months after treatment ends. - Participants not receiving treatment, are cancer survivors, or undergoing cancer treatment that does not have a clear completion date, will have up to 3 visits: - Before the start of treatment or whenever you begin the study. - At least 3 months after your first visit. - At least 3 months after your second visit. - At each study visit, participants will complete the following tasks (some of the tasks can be done from home or virtually): - Questionnaires about physical activity, fatigue, depression, and quality of life (can be done at home or virtually). - Have blood drawn. - Physical activity device and journals to study how fatigue affects physical activity. - Optional tests: - Computer games testing your memory, attention, and ability to follow directions. - Hand grip strength test to evaluate physical strength. - Treatment will not be provided under this study.

NCT ID: NCT00972400 Recruiting - Breast Cancer Clinical Trials

Fatigue in Breast Cancer Survivors

Start date: January 2009
Phase: N/A
Study type: Observational

RATIONALE: Gathering information over time from blood samples and measurements of activity, sleep, mood, and cognition may help doctors learn more about fatigue in breast cancer survivors and plan the best treatment. PURPOSE: This clinical trial is studying fatigue in breast cancer survivors.

NCT ID: NCT00336089 Recruiting - Breast Cancer Clinical Trials

Exercise Program or Health Education Program in Reducing Fatigue and Pain in Breast Cancer Survivors

Start date: January 2006
Phase: N/A
Study type: Interventional

RATIONALE: An exercise program or health education program may help relieve fatigue and pain and improve the quality of life in women who are breast cancer survivors. It is not yet known whether an exercise program is more effective than a health education program or no program in reducing fatigue and pain in women who are breast cancer survivors. PURPOSE: This randomized clinical trial is studying an exercise program to see how well it works in reducing fatigue and pain compared to a health education program or no program in women who are breast cancer survivors.

NCT ID: NCT00094133 Recruiting - Breast Cancer Clinical Trials

Hypnosis in Treating Hot Flashes in Breast Cancer Survivors

Start date: April 2006
Phase: N/A
Study type: Interventional

RATIONALE: Hypnosis may be effective in decreasing hot flashes in breast cancer survivors. PURPOSE: This randomized clinical trial is studying how well hypnosis works in treating hot flashes in breast cancer survivors.