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Calculi clinical trials

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NCT ID: NCT03719456 Completed - Renal Stone Clinical Trials

Prospective Assessment of Procedure-Related and Patient-Reported Outcomes After Retrograde Intrarenal Surgery (RIRS) for Renal Calculi Less Than 20 mm

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The investigators aim at this study to prospectively assess procedure-related outcomes after RIRS for renal calculi less than 20 mm, including stone free rate (SFR), predictors of successful outcome, complications types/rate, readmission rate and the need of auxiliary procedures. In addition, patient-reported outcomes after this modality of intervention are going to be assessed.

NCT ID: NCT03701009 Completed - Stone Clearance Clinical Trials

Saline Irrigation Reduces the Residual Bile Duct Stones During Endoscopic Retrograde Cholangiopancreatography (ERCP)

Start date: October 10, 2018
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate the usefulness of saline solution irrigation in decreasing residual common bile duct (CBD) stones.

NCT ID: NCT03692715 Recruiting - Nephrolithiasis Clinical Trials

Antibiotic Prophylaxis Before Shock Wave Lithotripsy

APPEAL
Start date: September 27, 2018
Phase: Phase 4
Study type: Interventional

This is a two arm, double blind RCT comparing the use of a single dose ciprofloxacin prior to SWL to saline alone. The multicenter trial will be conducted with a pragmatic emphasis including both high volume and low volume sites internationally.

NCT ID: NCT03685955 Withdrawn - Hypospadias Clinical Trials

Efficacy of Amniotic Membranes in Complex Genitourinary Reconstruction

Start date: March 2020
Phase:
Study type: Observational [Patient Registry]

Urinary fistulas are unfortunately one of the most common post operative complications in hypospadias repairs and bladder neck transections on pediatric and adult populations, an estimated 20%, resulting in multiple repeat operations with prolonged hospitalization. The negative sequelae of these fistulas have significant financial and psychosocial impact and the aim of this study is to evaluate if the fresh frozen preserved amniotic membrane tissue studied, which have live cells and intact naturally occurring growth hormones and peptides that augment healing that have been shown in early studies to be effective facilitating previous failed fistula repairs and leg ulcer healing, respectively, will help reduce the incidence of urinary fistulas in subject populations.

NCT ID: NCT03657667 Completed - Kidney Stone Clinical Trials

Evaluation of Pain Before and After Removal of Non-obstructive Kidney Stones

ENORC
Start date: August 28, 2018
Phase: N/A
Study type: Interventional

Pain associated with renal stone disease is typically caused by an obstructing stone that obstructs the flow of urine, which results in renal collecting system dilatation. Non-obstructing renal calculi that do not cause renal collecting system dilatation are thought to be painless. The objective of this study is to prospectively determine if the removal of non-obstructing renal calculi can reduce or eliminate participant's pain and/or improve their quality of life.

NCT ID: NCT03630926 Active, not recruiting - Prostate Cancer Clinical Trials

Evaluation of the NV-VPAC1 Prostate Cancer (PCa) Urine Diagnostic Test in Subjects With Biopsy-confirmed Prostate Cancer, Benign Prostatic Hypertrophy, or Bladder/Kidney Stones.

VPAC
Start date: October 16, 2018
Phase:
Study type: Observational

This is a double-blind, study to evaluate the performance of NV-VPAC1 PCa Urine Diagnostic Test in three distinct populations being treated at the Intermountain Urology Clinic. The first population (positive control) is comprised of men with biopsy-confirmed PCa who are scheduled for prostatectomy. The second population (negative control) is comprised of men with benign prostatic hypertrophy (BPH) who are scheduled for transurethral resection of the prostate (TURP). The third population (negative control) is comprised of men or women with bladder/kidney stones who are scheduled for a cystoscopy.

NCT ID: NCT03614247 Completed - Renal Calculi Clinical Trials

Cost-Effectiveness of Different Treatment Options for Lower Calyceal Stones

Start date: January 1, 2007
Phase: N/A
Study type: Interventional

The aim of the present study to perform a full cost analysis for the complete clearance of calyceal stones by retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PNL) for the treatment of lower calyceal stones between 1 and 2 centimeters (cm) in size.

NCT ID: NCT03614052 Terminated - Urolithiasis Clinical Trials

Tamsulosin as Adjuvant Treatment Prior to Endoscopic Ureterolithotomy

Start date: June 1, 2018
Phase: Phase 4
Study type: Interventional

This a study aiming to compare treatment with tamsulosin versus placebo in patients undergoing endoscopic treatment for urolithiasis. The main outcome is the rate of stone free patients.

NCT ID: NCT03608098 Withdrawn - Kidney Stone Clinical Trials

Long Pulse Versus Short Pulse Laser Dusting for Renal Stones

Start date: May 2019
Phase: N/A
Study type: Interventional

The purpose of this research study is to compare how well two treatments work for removing kidney stones. The two study groups include ureteroscopy with long/short pulse lithotripsy to remove kidney stones. Both of these options are considered standard of care and are used currently in surgery.

NCT ID: NCT03599297 Recruiting - Kidney Calculi Clinical Trials

Bilateral Synchronous Simultaneous Stone Surgery

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

Advancements in technology and endourological armamentarium provides multiple surgical options for complicated stone patients. To avoid multiple operations and shorten the total operation durations, bilateral synchronous simultaneous stone surgery (BSSSS) has been popularized in recent years. Our aim is to evaluate the preliminary outcomes of BSSSS in patients undergoing supine percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS).