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Portal Flow Pulsatility as a Risk Factor for Acute Kidney Injury After Cardiac Surgery — PP-AKI  

Acute Kidney Injury Clinical Trial

Official title:
Assessment of Portal Flow Using Bedside Doppler Ultrasonography for the Detection of Portal Pulsatility as a Risk Factor for Acute Kidney Injury in Cardiac Surgery Patients

Clinical Trial Summary

The purpose of this study is to evaluate the possible association between portal vein flow pulsatility and acute kidney injury after cardiac surgery. Participants will undergo assessment of portal vein flow and intra-renal blood flow using bedside Doppler ultrasound before surgery and daily for three days after cardiac surgery.

Clinical Trial Description

Acute kidney injury is a frequent complication after cardiac surgery. Venous congestion from right ventricular dysfunction and fluid overload can impair kidney perfusion resulting in the cardio-renal syndrome.

An increase in the variation of blood flow velocity in the portal vein during the cardiac cycle called portal pulsatility is a sign of congestive heart failure. Portal pulsatility occurs when increased central venous pressure results liver venous congestion. The presence of abnormal portal pulsatility could be used as a marker of venous congestions in other organs such as the kidneys. Discontinuous intra-renal vein flow is a risk factor for death or re-hospitalization in heart failure patients and could be seen in patients with portal pulsatility. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02831907
Study type Observational
Source Montreal Heart Institute
Contact
Status Completed
Phase N/A
Start date August 2016
Completion date July 31, 2017
View Details
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