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NCT ID: NCT05289895 Not yet recruiting - Pancreatic Cancer Clinical Trials

Prognostic Biomarkers of Pancreatic Cancer Based on Proteomic Techniques

Start date: April 1, 2022
Phase:
Study type: Observational

Sequence I (Retrospective study: proteomic analysis of pathological specimens and information collection of previous patients with pancreatic cancer) Sequence 2 (Non-interventional prospective study, sample and information collection in patients with pancreatic cancer) Sequence 3 (Non-intervention study, healthy subjects sample and information collection)

NCT ID: NCT05290532 Not yet recruiting - Clinical trials for Surgery--Complications

Effect of Multimodal Postoperative Rehabilitation on Functional and Cognitive Decline

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Older adults, especially those with frailty, have a higher risk for complications, functional and cognitive decline after urgent surgery. These patients have their functional and physiological reserve reduced which makes them more vulnerable to the effects of being bedridden. The consequences are at multiple levels emphasizing the functional loss or cognitive impairment, longer stays, mortality and institutionalization, delirium, poor quality of life and increased use of resources related to health. Exercise training can prevent functional and cognitive decline and modify even the posterior trajectory

NCT ID: NCT05291416 Not yet recruiting - Sarcopenia Clinical Trials

Sarcopenia in Children

Start date: April 1, 2022
Phase:
Study type: Observational

Juvenile idiopathic arthritis (AJI), is a frequent inflammatory disease in children, characterized by pain, arthritis, and deformities. Chronic inflammation leads to physical inactivity and can be associated with muscle weakness around affected joints, low bone strength, and mass(3). To our knowledge, no study has focused on the prevalence of sarcopenia in JIA and the data on the muscle disorder are lacking. The purpose of the present study is to detect sarcopenia and identify associated factors in children with JIA

NCT ID: NCT05291702 Not yet recruiting - Staghorn Calculi Clinical Trials

Multitract Percutaneous Nephrolithotomy(PCNL) in Large Renal Stones.

PCNL
Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Investigator aimed to analyze the clinical efficacy and safety of multiple tracts PCNL as one step therapy to treat the staghorn stones or multiple calyceal calculi which are inaccessible by single tract

NCT ID: NCT05292053 Not yet recruiting - Copd Clinical Trials

Outcomes of Once-Daily ICS/LABA/LAMA Plus PRN Respiratory Therapy Treatments in Hospitalized Patients With COPD Exacerbations

Sundial-COPD
Start date: April 1, 2022
Phase: Phase 4
Study type: Interventional

This is a single-center, prospective, open-label study evaluating outcomes of TRELEGY ELLIPTA (fluticasone furoate 100 mcg, umeclidinium 62.5 mcg, and vilanterol 25 mcg inhalation powder) on PRN nebulized short-acting beta agonist (SABA) treatment in hospitalized subjects with COPD with or without asthma. Approximately 80 adult subjects with COPD with or without asthma will take part in this study at this location. Subjects will be given TRELEGY ELLIPTA, placed on a consistent short-term systemic corticosteroid therapy, and followed until 30 days post hospital discharge. This study will not include patients with rapidly deteriorating or potentially life-threatening episodes of COPD or asthma.

NCT ID: NCT05293015 Not yet recruiting - Diabetes Clinical Trials

NP-Supported Multidisciplinary Diabetes Management During Perioperative Period

NPMDM-PP
Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The primary objective of this study is to determine the benefits of interventions from a Multidisciplinary Diabetes Care team involved of diabetes nurse practitioners(DNP) on glucose control, perioperative outcomes and psychosocial outcomes for patients with Diabetes Mellitus

NCT ID: NCT05294926 Not yet recruiting - Spine Fracture Clinical Trials

Comparison Of Deep Versus Moderate Neuromuscular Blockade on Intra-Operative Blood Loss During Spinal Surgery

Start date: April 1, 2022
Phase: Early Phase 1
Study type: Interventional

Reduction of intra-operative blood loss

NCT ID: NCT05295329 Not yet recruiting - Diabetes Clinical Trials

Effect of Compound Danshen Dripping Pills on Diabetic Patients With Coronary Microcirculation Disturbance

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Most patients with diabetes complicated with microvascular circulation disorder have normal coronary angiography but still suffer from chest tightness, chest pain and so on. Early dysfunction of coronary microcirculation is an important reason for it. It is also an important factor leading to poor prognosis of patients with diabetes. For these patients, there are still no drugs to improve microcirculation disorders. Compound Danshen dropping pills have the effects of anti-oxidation, anti-inflammatory, protecting endothelium, inhibiting the formation of atherosclerotic plaque and intimal hyperplasia, reducing oxygen consumption, improving energy metabolism, protecting cardiomyocytes, inhibiting platelet adhesion and aggregation, and improving microcirculation. However, there is a lack of clinical evidence that compound Danshen dripping pills can improve the cardiac microcirculation disturbance in diabetic patients with microangio angina. Therefore, the aim of this study was to observe the effect of Compound Danshen Dripping Pills on coronary microcirculation disturbance in diabetic patients.

NCT ID: NCT05295719 Not yet recruiting - Obesity Clinical Trials

Combining HIIT and n-3 PUFA to Reduce Inflammation and Improve Metabolic Health

HIIT&PUFA
Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The goal of this project is to understand the combined effects of fish oil and exercise in obesity-associated inflammation. The investigators hypothesize that fish oil will improve gut bacteria profiles, which will in turn potentiate the benefits of an exercise program and improve energy utilization and reduce inflammation and metabolic risk.

NCT ID: NCT05296434 Not yet recruiting - Clinical trials for Chronic Liver Disease

Delta Radiomics for Liver Function Evaluation

Start date: April 1, 2022
Phase:
Study type: Observational

To evaluate the feasibility and efficacy of delta radiomics-derived index based on Gd-EOB-DTPA enhanced MRI as a new imaging biomarker for the quantitative assessment of liver function.